{"id":"W2011256652","doi":"10.4137/grsb.s13946","title":"Tetracycline Derivative Minocycline Inhibits Autophagy and Inflammation in Concanavalin-A-Activated Human Hepatoma Cells","year":2014,"lang":"en","type":"article","venue":"Gene Regulation and Systems Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Minocycline; Autophagy; Vacuole; Gene silencing; Concanavalin A; Signal transduction; Cell biology; Inflammation; STAT3; Biology; Chemistry; Cancer research; Molecular biology; Biochemistry; Immunology; Gene; Apoptosis; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003087392,0.0001543093,0.0003912323,0.0001783445,0.00007377141,0.00001447437,0.00002736701,0.0002083775,0.00003559417],"category_scores_gemma":[0.00004183485,0.0001304557,0.00002788314,0.0001276151,0.0001087886,0.000060171,0.00001946628,0.00008764651,0.000005907197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003794353,"about_ca_system_score_gemma":0.00002556262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001165074,"about_ca_topic_score_gemma":0.00002897944,"domain_scores_codex":[0.9987636,0.0002367759,0.0004676902,0.0002843815,0.000075884,0.0001716641],"domain_scores_gemma":[0.9993821,0.00008625902,0.0001877057,0.0001560969,0.00007907379,0.0001087695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009319338,0.00003128244,0.02461091,0.00006939693,0.00004126054,0.000003791967,0.0002130683,0.00001972248,0.9671696,0.002962332,0.00002148785,0.004763947],"study_design_scores_gemma":[0.003107782,0.0003027918,0.3585476,0.00007048692,0.00002792598,0.00003434777,0.00005681049,0.00983376,0.6242676,0.0006019586,0.002986151,0.0001627939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979302,0.0004816224,0.0005576912,0.0002049236,0.0001311401,0.0004680608,0.00001028367,0.00004363998,0.0001724187],"genre_scores_gemma":[0.9989375,0.0000638431,0.000115032,0.0001166654,0.0002421646,0.00002408662,0.0002289557,0.00001401715,0.0002577032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.342902,"threshold_uncertainty_score":0.5319831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01849701418208709,"score_gpt":0.2900405716986565,"score_spread":0.2715435575165694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}