{"id":"W2011305479","doi":"10.1039/c2mb25348h","title":"Biochemical measurements on single erythroid progenitor cells shed light on the combinatorial regulation of red blood cell production","year":2012,"lang":"en","type":"article","venue":"Molecular BioSystems","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Downregulation and upregulation; Erythropoietin; Stem cell factor; Progenitor cell; Cell biology; Erythropoiesis; Biology; Bone marrow; Stem cell; Kinase; Molecular biology; Immunology; Biochemistry; Anemia; Endocrinology; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002441315,0.0004124514,0.0004038469,0.0003588702,0.0001033895,0.0004056844,0.0002027672,0.0002778057,0.0006928777],"category_scores_gemma":[0.0002394532,0.0001343237,0.0001931819,0.0003026651,0.0001970202,0.0003221716,0.0002399944,0.000646936,0.0003192261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001817133,"about_ca_system_score_gemma":0.0001521604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001413088,"about_ca_topic_score_gemma":0.0002601326,"domain_scores_codex":[0.9997301,0.00003056101,0.00002744497,0.00008935288,0.00009784738,0.00002471337],"domain_scores_gemma":[0.9997469,0.00006916554,0.00004817775,0.00002929263,0.00005804272,0.00004853973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001323481,0.00000580262,0.0002281898,0.0000152752,0.00000186466,0.000007311015,0.000005836992,0.00002804914,0.9988034,0.0000266386,0.000005761694,0.0008586004],"study_design_scores_gemma":[0.000001885515,0.00006876675,0.004685882,0.000002340388,0.000009457832,0.00006301774,0.00001066577,0.0006040188,0.9941152,0.0000493445,0.0003865302,0.000002854802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9506218,0.002817634,0.04282058,0.00007590568,0.000033299,0.00006108256,0.001265481,0.0002404618,0.002063764],"genre_scores_gemma":[0.9649053,0.001692114,0.02936421,0.00006301751,0.0000198755,0.0001232589,0.00122397,0.0000858098,0.002522425],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006928777,"threshold_uncertainty_score":0.002317905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02357455969017327,"score_gpt":0.2270757480520275,"score_spread":0.2035011883618543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}