{"id":"W2011337290","doi":"10.1111/j.1462-5822.2007.00976.x","title":"The carboxyl-terminal SH3 domain of the mammalian adaptor CrkII promotes internalization of Listeria monocytogenes through activation of host phosphoinositide 3-kinase","year":2007,"lang":"en","type":"article","venue":"Cellular Microbiology","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Internalization; Cell biology; Signal transducing adaptor protein; Biology; Signal transduction; Listeria monocytogenes; SH3 domain; Listeria; Kinase; Actin cytoskeleton; Protein kinase domain; Tyrosine kinase; Cytoskeleton; Receptor; Cell; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002117973,0.0001468845,0.0001800569,0.00002432112,0.0001023512,0.000006900332,0.0002968224,0.000168805,0.00001445017],"category_scores_gemma":[0.00005434777,0.00009631341,0.0001696994,0.00009672869,0.0003502546,0.000005885465,0.0001815717,0.00006023925,5.314741e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001571559,"about_ca_system_score_gemma":0.00006031133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001364738,"about_ca_topic_score_gemma":0.0000557801,"domain_scores_codex":[0.998966,0.0001369819,0.0004287246,0.0002216029,0.00005505984,0.0001916172],"domain_scores_gemma":[0.9989207,0.0000318751,0.0004563473,0.0004057853,0.0001585986,0.0000267075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003370268,0.00008614042,0.005619091,0.00005657279,0.00005381171,0.000001129264,0.0001195515,0.00001167721,0.9930297,0.0002193301,0.0002790146,0.0001869998],"study_design_scores_gemma":[0.0003660859,0.0003310724,0.001523111,0.00006081505,0.00002396404,0.00001585871,0.000138543,0.000003767849,0.9929888,0.000166101,0.004281723,0.0001001568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910673,0.001081019,0.007002781,0.00003682073,0.000342945,0.0002622832,0.00006939426,0.000003840538,0.0001336327],"genre_scores_gemma":[0.999316,0.00007103048,0.0002205204,0.00005245737,0.0001000327,0.000008214717,0.00009606665,0.00001592409,0.0001198005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008248669,"threshold_uncertainty_score":0.3927547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009423370998460634,"score_gpt":0.2433960580742818,"score_spread":0.2339726870758212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}