{"id":"W2011387212","doi":"10.1016/j.chroma.2008.02.016","title":"Purification of a human immunoglobulin G1 monoclonal antibody from transgenic tobacco using membrane chromatographic processes","year":2008,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph; McMaster University","funders":"","keywords":"Chemistry; Chromatography; Monoclonal antibody; Membrane; Affinity chromatography; Ion chromatography; Antibody; Membrane protein; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003032181,0.0004087932,0.0004196873,0.0003220442,0.0003015849,0.0004304752,0.0004698379,0.0005035316,0.0008533242],"category_scores_gemma":[0.0002071034,0.0002474623,0.0005566486,0.0004213818,0.0001816154,0.0002478704,0.0003006258,0.00106597,0.001031363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000738878,"about_ca_system_score_gemma":0.000405985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002344755,"about_ca_topic_score_gemma":0.002621164,"domain_scores_codex":[0.9998749,0.00001186131,0.00001163486,0.00003321507,0.00003735454,0.00003097547],"domain_scores_gemma":[0.9998542,0.00003623511,0.00001902099,0.00001888359,0.00003937089,0.00003219187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001307799,0.000008733855,0.0000616473,0.00001553887,0.000003362692,0.00001748567,0.000006609701,0.00001271212,0.9990842,0.00005554263,0.00003777434,0.0006833265],"study_design_scores_gemma":[0.00001165717,0.00004581552,0.00205431,0.000006075174,0.00002627837,0.0001440103,0.00001417519,0.0007764932,0.9928059,0.00008815355,0.0040227,0.00000453572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8973113,0.003055342,0.08971144,0.0008812834,0.0002605534,0.0002343649,0.001859255,0.0009135769,0.005772871],"genre_scores_gemma":[0.9274513,0.003512645,0.04767766,0.0005428916,0.00006680741,0.0001559065,0.006354704,0.0002746532,0.01396343],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002344755,"threshold_uncertainty_score":0.005360961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02188583250897554,"score_gpt":0.2784200404889104,"score_spread":0.2565342079799349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}