{"id":"W2011486878","doi":"10.1371/journal.pone.0108921","title":"Distinctive PSA-NCAM and NCAM Hallmarks in Glutamate-Induced Dendritic Atrophy and Synaptic Disassembly","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Secretaría de Ciencia y Técnica, Universidad de Buenos Aires; Agencia Nacional de Promoción Científica y Tecnológica; Universidad de Buenos Aires; Consejo Nacional de Investigaciones Científicas y Técnicas","keywords":"Neural cell adhesion molecule; Synapse; Synaptophysin; Hippocampal formation; Dendritic spine; Neuroscience; NMDA receptor; Glutamate receptor; Synaptic plasticity; Biology; Neuroplasticity; Neurogenesis; Cell biology; Hippocampus; Chemistry; Receptor; Immunology; Cell adhesion; Cell; Biochemistry; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009197811,0.0004005658,0.0003760947,0.0005992322,0.0002283864,0.0002559737,0.0002289346,0.0004329269,0.001053674],"category_scores_gemma":[0.0001515373,0.0002253035,0.0004701643,0.0003280265,0.000329505,0.0003311482,0.0003455331,0.0008463024,0.0003611759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003081652,"about_ca_system_score_gemma":0.0002294522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007108177,"about_ca_topic_score_gemma":0.0008710626,"domain_scores_codex":[0.9998339,0.000009230866,0.00001476573,0.00003134951,0.00007351874,0.00003707766],"domain_scores_gemma":[0.9997899,0.00001161367,0.00007305841,0.00001608937,0.00003964725,0.00006963249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001266534,0.00001681765,0.0004994753,0.0000363123,0.000009362573,0.0002780821,0.00001679742,0.00001607269,0.9981614,0.00007106382,0.00002274191,0.0007452554],"study_design_scores_gemma":[0.00003548739,0.000893999,0.1854817,0.00001992434,0.00007641708,0.008054825,0.0001316369,0.0009845437,0.8013914,0.0005230848,0.002378751,0.00002825812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869682,0.00445662,0.004694415,0.0001125638,0.00006643717,0.00006694152,0.0007901755,0.0001615367,0.002683017],"genre_scores_gemma":[0.9913098,0.001460175,0.003141451,0.00011079,0.00002905888,0.0001064454,0.0008934328,0.00002077937,0.002928089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001053674,"threshold_uncertainty_score":0.00352484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06602561922597323,"score_gpt":0.2919256629457628,"score_spread":0.2259000437197896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}