{"id":"W2011492248","doi":"10.1016/j.tem.2012.04.004","title":"Mitochondrial proticity and ROS signaling: lessons from the uncoupling proteins","year":2012,"lang":"en","type":"review","venue":"Trends in Endocrinology and Metabolism","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Mitochondrion; ATP synthase; Electrochemical gradient; Reactive oxygen species; Context (archaeology); Mitochondrial ROS; Oxidative phosphorylation; Chemiosmosis; Cell biology; Inner mitochondrial membrane; Biology; Chemistry; Biochemistry; Membrane; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001715003,0.0004786364,0.001087758,0.0001624536,0.0001678124,0.00003032523,0.0002725103,0.0006740991,0.0001076283],"category_scores_gemma":[0.0001175623,0.0003270545,0.00020681,0.0001688549,0.0003251328,0.00000695789,0.0003073707,0.0007045203,0.00001012393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000916801,"about_ca_system_score_gemma":0.00008131326,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001084552,"about_ca_topic_score_gemma":0.0002378987,"domain_scores_codex":[0.9975771,0.0005144309,0.0004993251,0.000752832,0.00009213276,0.0005641307],"domain_scores_gemma":[0.9990028,0.0001188318,0.0002395756,0.0004949031,0.00002880568,0.0001150962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007644292,0.00007539389,0.00009812741,0.0002255556,0.0002190762,0.00001532289,0.0001064724,0.000001060602,0.002270626,0.001838302,0.000409744,0.9946639],"study_design_scores_gemma":[0.0007493742,0.00006026309,0.0001796277,0.0001602793,0.0006684377,0.000151718,0.00001873328,7.407387e-7,0.0003561571,0.0001388079,0.9971827,0.0003331267],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001477853,0.9953141,0.0001936994,0.0001632784,0.001765246,0.0006487535,0.0001431694,0.00001987523,0.0002739865],"genre_scores_gemma":[0.0005471241,0.9936733,0.00101721,0.0001138799,0.002712501,0.0004701834,0.000447031,0.00004736368,0.0009713832],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.996773,"threshold_uncertainty_score":0.9999182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06789706976144128,"score_gpt":0.3366558234466383,"score_spread":0.268758753685197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}