{"id":"W2011494353","doi":"10.1016/j.bone.2007.09.047","title":"Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading","year":2007,"lang":"en","type":"article","venue":"Bone","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":355,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute on Aging; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Aeronautics and Space Administration","keywords":"Osteocyte; Osteoclast; Chemistry; Cell biology; Bone resorption; Stromal cell; RANKL; Bone remodeling; Bone cell; Bone marrow; Osteoblast; Internal medicine; In vitro; Endocrinology; Biology; Biochemistry; Activator (genetics); Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005071834,0.0003360201,0.0003955754,0.0002392451,0.0002334499,0.000537521,0.000244425,0.0005568932,0.000641149],"category_scores_gemma":[0.0003432617,0.0002919601,0.0002047912,0.0001698036,0.0005998439,0.0003576923,0.0004093918,0.0006496899,0.0001838405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002690089,"about_ca_system_score_gemma":0.0003466964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007609175,"about_ca_topic_score_gemma":0.001259966,"domain_scores_codex":[0.9997478,0.00006513733,0.00001683956,0.00001982441,0.00009353529,0.00005688779],"domain_scores_gemma":[0.9998036,0.0000743331,0.00002497162,0.00001860045,0.0000371688,0.00004125644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004719791,0.00001691061,0.0003419806,0.0000872283,0.000008793998,0.0003398178,0.00003678503,0.0001541092,0.9941657,0.00107262,0.00007482622,0.003229433],"study_design_scores_gemma":[0.0001463799,0.0004827607,0.01376456,0.00003050122,0.00005570235,0.001052668,0.0001193423,0.001499229,0.9740474,0.001345725,0.007440891,0.00001478164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9333892,0.04815098,0.01172756,0.0007928365,0.0002023357,0.00007338744,0.0002328117,0.0001155052,0.005315462],"genre_scores_gemma":[0.9842906,0.008849482,0.003269475,0.0001818631,0.00005637102,0.00005399704,0.0000887531,0.0000181267,0.003191462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007609175,"threshold_uncertainty_score":0.002682328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009952323384028045,"score_gpt":0.2564876328669398,"score_spread":0.2465353094829117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}