{"id":"W2011520905","doi":"10.1016/j.ab.2004.04.023","title":"Validation and characterization of uninhibited enzyme kinetics performed in multiwell plates","year":2004,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Microfluidic and Capillary Electrophoresis Applications","field":"Engineering","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Enzyme kinetics; Experimental data; Substrate (aquarium); Kinetics; Biological system; Chemistry; Enzyme; MATLAB; Enzyme assay; Chromatography; Computer science; Analytical Chemistry (journal); Biochemistry; Mathematics; Statistics; Physics; Biology; Active site","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002900932,0.00007318919,0.00009405896,0.00003752113,0.00001030445,0.000007047038,0.00003976278,0.00008255796,0.00002371988],"category_scores_gemma":[0.00001235956,0.00007655242,0.00001678072,0.0001806972,0.00004026808,0.00002401184,0.000009565243,0.00006651565,0.000002978358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003853029,"about_ca_system_score_gemma":0.00001059532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003704383,"about_ca_topic_score_gemma":2.136489e-7,"domain_scores_codex":[0.9995654,0.000002593093,0.0001745693,0.00009896474,0.00005769471,0.0001008263],"domain_scores_gemma":[0.9998139,0.00001156825,0.00001832041,0.00009457879,0.00002230754,0.00003932605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000003386343,0.00002702106,0.0003561862,0.00004835278,0.000007521493,4.118165e-7,0.00002709099,0.00006276762,0.9991597,0.0001426494,0.00003430606,0.0001306198],"study_design_scores_gemma":[0.0002312166,0.00001186474,0.001980113,0.00002235978,0.00001171754,0.000002633756,0.00001174732,0.002882268,0.9945891,0.00006262869,0.0001170489,0.00007724234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984919,0.0005442985,0.0005923551,0.0000589363,0.000004985899,0.00005017138,0.000009539995,0.00002516818,0.000222584],"genre_scores_gemma":[0.9966134,0.003110707,0.00003930236,0.0000105339,0.00001538491,0.000004186896,0.0001729689,0.000008336556,0.00002521181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004570527,"threshold_uncertainty_score":0.3121717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004638089880678323,"score_gpt":0.194071312826022,"score_spread":0.1894332229453437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}