{"id":"W2011533283","doi":"10.1053/meta.2001.23303","title":"Hepatic cholesterol and bile acid synthesis, low-density lipoprotein receptor function, and plasma and fecal sterol levels in mice: Effects of apolipoprotein E deficiency and probucol or phytosterol treatment","year":2001,"lang":"en","type":"article","venue":"Metabolism","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Probucol; Internal medicine; Phytosterol; Cholesterol; Endocrinology; Sterol; Apolipoprotein B; LDL receptor; Bile acid; Chemistry; Feces; Lipoprotein; Biology; Biochemistry; Medicine; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004806379,0.0005453015,0.001290046,0.0003759165,0.0001343878,0.00007887819,0.0000767706,0.0002626621,0.00002658077],"category_scores_gemma":[0.000299084,0.0003944783,0.0000719657,0.0003169522,0.0003146455,0.0002990432,0.0001306558,0.0002603978,0.000005077239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004588101,"about_ca_system_score_gemma":0.00006928145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006699719,"about_ca_topic_score_gemma":0.0004934311,"domain_scores_codex":[0.9973508,0.0003105928,0.0006449003,0.0008224884,0.0003480057,0.000523285],"domain_scores_gemma":[0.9986904,0.0002306756,0.0002320661,0.0003909895,0.00008201822,0.0003738511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.002735967,0.001092656,0.05856878,0.002358449,0.0001850934,0.00006106321,0.002452536,8.165801e-7,0.4325288,0.00005148281,0.00001768221,0.4999467],"study_design_scores_gemma":[0.01154486,0.001006634,0.8098722,0.0007453,0.0006349899,0.0003655182,0.0001622802,0.000158147,0.1737922,0.0000827574,0.001245231,0.0003898957],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890137,0.007068731,0.00007348954,0.0003596945,0.0002559646,0.003117227,0.00003057827,0.00005350817,0.00002710726],"genre_scores_gemma":[0.9960364,0.001914483,0.0006091073,0.0002284508,0.0002937646,0.0005608526,0.000005454307,0.00005496538,0.0002965323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7513034,"threshold_uncertainty_score":0.9998507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01269303922133701,"score_gpt":0.2357994223205131,"score_spread":0.223106383099176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}