{"id":"W2011597399","doi":"10.1016/j.virol.2009.06.050","title":"The Elav-like protein HuR exerts translational control of viral internal ribosome entry sites","year":2009,"lang":"en","type":"article","venue":"Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias; National Cancer Institute; Comisión Nacional de Investigación Científica y Tecnológica; Universidad Andrés Bello; Pontificia Universidad Católica de Chile; Universidad de Chile; Terry Fox Foundation","keywords":"Internal ribosome entry site; Biology; Gene knockdown; Cell biology; Repressor; Translational regulation; Translation (biology); Messenger RNA; Activator (genetics); Reticulocyte; Molecular biology; Ribosome; Protein biosynthesis; Virology; RNA; Gene expression; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001736641,0.0001221587,0.0002180554,0.00006222272,0.0001607798,0.000006822909,0.000208387,0.0001667975,0.0005153754],"category_scores_gemma":[0.00003571956,0.00007871036,0.0001008955,0.00004497376,0.0003276879,0.0000418928,0.00001729362,0.0002379172,0.0004951298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001377818,"about_ca_system_score_gemma":0.00004923737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002579557,"about_ca_topic_score_gemma":0.000034896,"domain_scores_codex":[0.9988627,0.0002784033,0.0002446812,0.0001839198,0.00004563045,0.0003846473],"domain_scores_gemma":[0.9994859,0.0001928035,0.0000745173,0.000181418,0.0000398088,0.00002557446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001801437,0.0003078446,0.004412825,0.000003728102,0.000296888,0.00002890512,0.0001478149,0.000005186661,0.9700695,0.006501279,0.001480105,0.01494444],"study_design_scores_gemma":[0.02215988,0.007903092,0.5719224,0.00004184223,0.000152835,0.0004464612,0.00008624422,0.00006842005,0.2324374,0.01668433,0.1476091,0.0004880256],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880428,0.004801851,0.0005269399,0.004420371,0.0001485913,0.0004400301,0.0001127619,0.00002835709,0.001478241],"genre_scores_gemma":[0.9970901,0.0000480576,0.00002660078,0.0002187599,0.00003297085,0.00003937505,0.00009561748,0.000005353388,0.002443149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7376322,"threshold_uncertainty_score":0.6364057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006688969856975725,"score_gpt":0.2386422459815911,"score_spread":0.2319532761246154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}