{"id":"W2011597399","doi":"10.1016/j.virol.2009.06.050","title":"The Elav-like protein HuR exerts translational control of viral internal ribosome entry sites","year":2009,"lang":"en","type":"article","venue":"Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Fondo de Financiamiento de Centros de Investigación en Áreas Prioritarias; National Cancer Institute; Comisión Nacional de Investigación Científica y Tecnológica; Universidad Andrés Bello; Pontificia Universidad Católica de Chile; Universidad de Chile; Terry Fox Foundation","keywords":"Internal ribosome entry site; Biology; Gene knockdown; Cell biology; Repressor; Translational regulation; Translation (biology); Messenger RNA; Activator (genetics); Reticulocyte; Molecular biology; Ribosome; Protein biosynthesis; Virology; RNA; Gene expression; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002212883,0.0003761182,0.000257866,0.0002866545,0.0005489385,0.00070948,0.0001702285,0.0002325649,0.001838447],"category_scores_gemma":[0.0003262836,0.0001698217,0.0003205653,0.0001299878,0.0004643296,0.0002645434,0.000315384,0.0006176979,0.0007598925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006917406,"about_ca_system_score_gemma":0.0003618347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008065431,"about_ca_topic_score_gemma":0.002009789,"domain_scores_codex":[0.9998063,0.00003294239,0.000008684126,0.00003775574,0.00004236733,0.00007199918],"domain_scores_gemma":[0.9997895,0.00005230342,0.00004189153,0.00003180966,0.00003484086,0.00004973096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002111854,0.00002271722,0.0002864331,0.00002362887,0.000004221979,0.00007055466,0.00003391046,0.00009159005,0.9952291,0.0006728355,0.0001290322,0.003224734],"study_design_scores_gemma":[0.00001692643,0.0001686351,0.006291522,0.000008116776,0.000009594513,0.0001214574,0.00007750687,0.0008388535,0.9897847,0.0002652871,0.002410746,0.000006881384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849438,0.003672803,0.002965474,0.000308681,0.0001234541,0.00001249205,0.0001590861,0.0001668901,0.007647383],"genre_scores_gemma":[0.9942707,0.0007343887,0.001030039,0.00007844928,0.00005688982,0.000006618783,0.0002083054,0.00005382365,0.003560728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001838447,"threshold_uncertainty_score":0.006150186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006688969856975725,"score_gpt":0.2386422459815911,"score_spread":0.2319532761246154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}