{"id":"W2011622850","doi":"10.1371/journal.ppat.1001223","title":"H2A.Z Demarcates Intergenic Regions of the Plasmodium falciparum Epigenome That Are Dynamically Marked by H3K9ac and H3K4me3","year":2010,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Malaria Research and Control","field":"Medicine","cited_by":255,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; ZonMw; European Commission","keywords":"Epigenome; H3K4me3; Biology; Epigenetics; Genetics; Histone; Epigenomics; Computational biology; DNA methylation; Gene; Promoter; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000277023,0.0001962895,0.0003974304,0.00008578678,0.0001262678,0.0000209361,0.0002945418,0.0001615278,0.0003787975],"category_scores_gemma":[0.0006365561,0.0001288921,0.0001791841,0.0001630018,0.0002967094,0.00004919721,0.0002032591,0.0005409211,0.00001945117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002826553,"about_ca_system_score_gemma":0.000113904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002883977,"about_ca_topic_score_gemma":0.0002817253,"domain_scores_codex":[0.9983963,0.0001126186,0.0002796878,0.0003415751,0.0004100252,0.0004597917],"domain_scores_gemma":[0.9985223,0.0002040111,0.0001378961,0.0006753543,0.0001464788,0.0003139051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004309556,0.0003579902,0.1394358,0.0001532347,0.0002620968,0.00002609416,0.0001800155,2.586522e-7,0.8556978,0.0007451712,0.001789899,0.0009207321],"study_design_scores_gemma":[0.005727145,0.0008391171,0.9017777,0.0003874499,0.0008585452,0.00014296,0.0006656445,0.007470741,0.07051834,0.002133317,0.008808331,0.0006706637],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836298,0.0004333807,0.0001514183,0.01323082,0.0001341107,0.0007829909,0.0003082828,0.00004188171,0.001287339],"genre_scores_gemma":[0.996799,0.0001265706,0.0002609762,0.0002663624,0.00006749797,0.00008138208,0.00003245203,0.00003221423,0.002333551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7851794,"threshold_uncertainty_score":0.5256068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01467620779604525,"score_gpt":0.2366791891544221,"score_spread":0.2220029813583768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}