{"id":"W2011638907","doi":"10.3390/molecules20033758","title":"Tyrosol Prevents Ischemia/Reperfusion-Induced Cardiac Injury in H9c2 Cells: Involvement of ROS, Hsp70, JNK and ERK, and Apoptosis","year":2015,"lang":"en","type":"article","venue":"Molecules","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Agriculture and Agri-Food Canada; Fundamental Research Funds for the Central Universities; Ministry of Education, India","keywords":"Tyrosol; Apoptosis; DAPI; Myocyte; Chemistry; Oxidative stress; MAPK/ERK pathway; Cytoprotection; Reactive oxygen species; Hsp70; Molecular biology; Caspase 3; MTT assay; Caspase 8; Cell biology; Biochemistry; Heat shock protein; Biology; Kinase; Programmed cell death; Antioxidant","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000183366,0.0006608233,0.0005886029,0.0002502827,0.0001936951,0.0002255139,0.0002080667,0.0004034623,0.0007845912],"category_scores_gemma":[0.0001033474,0.0001813676,0.0003822575,0.0001753669,0.0002340702,0.0003030136,0.0002060889,0.0006960061,0.0001524669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001446978,"about_ca_system_score_gemma":0.0003090871,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004582601,"about_ca_topic_score_gemma":0.0007818353,"domain_scores_codex":[0.9998912,0.00001791052,0.00001810055,0.00001940108,0.00001856154,0.00003484001],"domain_scores_gemma":[0.9999037,0.000008515315,0.00003006231,0.000009846412,0.00001538065,0.00003249829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009009855,0.0001646786,0.0001494836,0.0001239453,0.0000150214,0.00007737006,0.00002205152,0.00004838053,0.9970335,0.00004705647,0.00004977487,0.001367737],"study_design_scores_gemma":[0.0001216969,0.001776244,0.003483424,0.00001633891,0.00004650636,0.0001915679,0.00003879887,0.0007021679,0.9924114,0.00003642273,0.00116725,0.000008243285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913896,0.005773273,0.001505136,0.0001439702,0.00007066273,0.00003134019,0.0002475161,0.00007144157,0.0007671599],"genre_scores_gemma":[0.9928181,0.002947825,0.001671223,0.0001124365,0.00004320424,0.00007133827,0.000475593,0.00002074089,0.00183958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007845912,"threshold_uncertainty_score":0.00262475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02096065100080724,"score_gpt":0.2813680706960639,"score_spread":0.2604074196952567,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}