{"id":"W2011711268","doi":"10.1038/clpt.2008.57","title":"Toward Personalized Therapy for Smoking Cessation: A Randomized Placebo-controlled Trial of Bupropion","year":2008,"lang":"en","type":"article","venue":"Clinical Pharmacology & Therapeutics","topic":"Smoking Behavior and Cessation","field":"Medicine","cited_by":182,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Cancer Institute; National Institute on Drug Abuse","keywords":"Bupropion; Placebo; Smoking cessation; Medicine; Quartile; Cotinine; Randomized controlled trial; Internal medicine; Clinical trial; Pharmacology; Nicotine; Anesthesia; Alternative medicine; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002298825,0.0002311876,0.001667484,0.0001118287,0.0001395777,0.000006648968,0.000145743,0.0003950723,0.0003630417],"category_scores_gemma":[0.0001576556,0.0001689582,0.001053229,0.0001421397,0.0007885055,0.00005473585,0.00001719193,0.0004012321,0.000001587228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005356906,"about_ca_system_score_gemma":0.0003317123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003369873,"about_ca_topic_score_gemma":1.005129e-7,"domain_scores_codex":[0.9969205,0.0008092694,0.00129871,0.0003493078,0.000354935,0.0002672481],"domain_scores_gemma":[0.9955099,0.0031772,0.0006111033,0.0001983605,0.0003988465,0.0001046382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9861062,0.001582045,0.003310186,0.00002253265,0.001809128,0.000008775147,0.0007382315,0.000003526115,0.002135512,0.00004099888,0.000903423,0.003339401],"study_design_scores_gemma":[0.9848545,0.002142654,0.00155677,0.00001900452,0.002828443,0.00001923823,0.0000574231,0.0006960729,0.002870951,0.0001752385,0.004623244,0.0001564996],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811721,0.0005204162,0.002410435,0.005076485,0.003154744,0.007377422,0.00000610714,0.00008810421,0.0001941828],"genre_scores_gemma":[0.9804503,0.004625328,0.0003358773,0.0116693,0.001331055,0.001145924,0.00004024344,0.00003871733,0.0003632696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00659282,"threshold_uncertainty_score":0.6889917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1958475682510731,"score_gpt":0.4507949521844458,"score_spread":0.2549473839333727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}