{"id":"W2011712807","doi":"10.1182/blood-2008-12-192054","title":"Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":339,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; BC Cancer Agency","funders":"Institute of Genetics; National Cancer Institute; Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; Terry Fox Foundation; BC Cancer Agency; Austrian Science Fund; Michael Smith Health Research BC; Stem Cell Network","keywords":"Stem cell; Biology; Haematopoiesis; Cell biology; Induced pluripotent stem cell; CXCR4; Stem cell theory of aging; Immunology; Bone marrow; Genetics; Stem cell factor; Embryonic stem cell; Gene; Immune system; Chemokine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001736148,0.0001477001,0.0001896702,0.0003308333,0.0001375666,0.0003976247,0.0001849136,0.0001798081,0.0007167824],"category_scores_gemma":[0.0002799779,0.0001029314,0.0001345204,0.0002523604,0.0001770986,0.0002103519,0.0002522276,0.0003337252,0.0004553437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009769854,"about_ca_system_score_gemma":0.0001672891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001828862,"about_ca_topic_score_gemma":0.0003268235,"domain_scores_codex":[0.9999192,0.00001000735,0.00001106935,0.00001763922,0.00002782496,0.00001429675],"domain_scores_gemma":[0.9998559,0.00003064726,0.00003074793,0.00002817343,0.00002486166,0.00002966626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000387191,0.00001219262,0.001185717,0.00002338545,0.000002207024,0.00004182845,0.00001795602,0.00004278773,0.9938111,0.0001880132,0.00002401621,0.004612064],"study_design_scores_gemma":[0.00002297202,0.0005032372,0.040699,0.00002150506,0.00005685119,0.001442894,0.0001384043,0.001356438,0.9453687,0.0003930401,0.009987225,0.000009767436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9763783,0.002890041,0.01723093,0.0001332582,0.00001675313,0.0001302642,0.001085062,0.00006380592,0.002071534],"genre_scores_gemma":[0.9757845,0.002097315,0.01637306,0.00008518202,0.00002833035,0.00008851651,0.003554847,0.00003094228,0.001957262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007167824,"threshold_uncertainty_score":0.002397835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003654790148121671,"score_gpt":0.1936247957300124,"score_spread":0.1899700055818907,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}