{"id":"W2011735277","doi":"10.1210/en.2002-220403","title":"Characterization of the Biological Roles of the Estrogen Receptors, ERα and ERβ, in Estrogen Target Tissues<i>in Vivo</i>through the Use of an ERα-Selective Ligand","year":2002,"lang":"en","type":"article","venue":"Endocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":369,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute","keywords":"Endocrinology; Internal medicine; Estrogen receptor; Estrogen; Estrogen receptor beta; Estrogen receptor alpha; Agonist; Receptor; In vivo; Biology; Hypothalamus; Chemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007062563,0.0001441891,0.00023695,0.00003239088,0.00004684264,0.000004568695,0.000267714,0.0002031178,0.00001139232],"category_scores_gemma":[0.0001072733,0.00007785187,0.00007685427,0.0001945624,0.000437172,0.00001044782,0.0001668478,0.0001967976,4.985255e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009271136,"about_ca_system_score_gemma":0.00002281255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008371285,"about_ca_topic_score_gemma":0.00004959114,"domain_scores_codex":[0.9987258,0.0004005839,0.0003060233,0.0002480578,0.00007766254,0.0002418305],"domain_scores_gemma":[0.9993508,0.0000469957,0.0002061984,0.0003333771,0.00004192374,0.00002071376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008744792,0.000138448,0.07009065,0.000007716252,0.0000513495,0.000002129772,0.0004405879,0.00007503945,0.9277722,0.0004084315,0.00004772754,0.0008782955],"study_design_scores_gemma":[0.0004752562,0.0003967509,0.01437466,0.00001792922,0.00001693413,0.00004228501,0.0000662483,0.00006964019,0.9785914,0.00009937194,0.005768505,0.00008099503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973618,0.001794103,0.000009796116,0.0002761601,0.0001003174,0.0003551514,0.00003335613,0.000003869503,0.00006548652],"genre_scores_gemma":[0.9983195,0.001319262,0.0001376689,0.00006889163,0.0000361313,0.00001889985,0.00001833705,0.00001148447,0.000069827],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05571599,"threshold_uncertainty_score":0.3174707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01579076136074569,"score_gpt":0.2288319624317168,"score_spread":0.2130412010709711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}