{"id":"W2011735277","doi":"10.1210/en.2002-220403","title":"Characterization of the Biological Roles of the Estrogen Receptors, ERα and ERβ, in Estrogen Target Tissues<i>in Vivo</i>through the Use of an ERα-Selective Ligand","year":2002,"lang":"en","type":"article","venue":"Endocrinology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":369,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute","keywords":"Endocrinology; Internal medicine; Estrogen receptor; Estrogen; Estrogen receptor beta; Estrogen receptor alpha; Agonist; Receptor; In vivo; Biology; Hypothalamus; Chemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002050878,0.0003071685,0.0002354176,0.0001330051,0.0001258495,0.0002216367,0.0001845789,0.0002048414,0.001114816],"category_scores_gemma":[0.0001211616,0.0001529912,0.0001663684,0.00009773236,0.0002099559,0.0002850317,0.00009110397,0.000503079,0.0004228929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001836726,"about_ca_system_score_gemma":0.0001703053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003090067,"about_ca_topic_score_gemma":0.0005671613,"domain_scores_codex":[0.9999369,0.0000127778,0.00000599688,0.00001376748,0.00001475723,0.00001578064],"domain_scores_gemma":[0.9999285,0.00001555898,0.00002339952,0.00001064344,0.00001142006,0.00001050309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001093574,0.00001829213,0.0001799691,0.00002844807,0.000002406845,0.00001987864,0.00000577039,0.00002960527,0.9981896,0.00004993863,0.00001277713,0.001353975],"study_design_scores_gemma":[0.00001817186,0.000802082,0.004547793,0.000009734164,0.00002338133,0.0003357914,0.00004096267,0.0002480433,0.9912784,0.0000440869,0.00264867,0.000002886252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9762045,0.007537507,0.01287323,0.0003005086,0.00003696599,0.00006309993,0.0004311119,0.00006888423,0.002484166],"genre_scores_gemma":[0.9737754,0.008516957,0.01051568,0.0001726643,0.00004285447,0.0000733049,0.0009618867,0.00002214407,0.005919125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001114816,"threshold_uncertainty_score":0.003729403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01579076136074569,"score_gpt":0.2288319624317168,"score_spread":0.2130412010709711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}