{"id":"W2011795666","doi":"10.1016/j.eplepsyres.2008.07.021","title":"Re: Epilepsy Res 2008;79(May (2–3)):97–104","year":2008,"lang":"en","type":"article","venue":"Epilepsy Research","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Active site; Chalcone; Stereochemistry; Hydrazone; Quantitative structure–activity relationship; Moiety; Aldol condensation; Docking (animal); Biological activity; Hydrazide; Pyridine; Pharmacophore; Combinatorial chemistry; Enzyme; Medicinal chemistry; Organic chemistry; Biochemistry; Catalysis; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001098611,0.001221766,0.001413449,0.002004472,0.0009527879,0.004082482,0.001462279,0.001641131,0.2917006],"category_scores_gemma":[0.002340295,0.0003552166,0.0006316759,0.001352256,0.001186728,0.002519069,0.001089079,0.002296972,0.1798373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001579879,"about_ca_system_score_gemma":0.001231038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004102204,"about_ca_topic_score_gemma":0.0125091,"domain_scores_codex":[0.9996067,0.0000515636,0.00004988972,0.00005904527,0.0001746981,0.00005813008],"domain_scores_gemma":[0.9990533,0.0001093403,0.00009267317,0.0001806932,0.0003904519,0.0001735808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004774147,0.0001239649,0.001946232,0.0004349657,0.0001110832,0.0007607461,0.00005985352,0.0002072589,0.003972492,0.004904267,0.5959483,0.3910533],"study_design_scores_gemma":[0.0002269428,0.0001759082,0.009340049,0.0006430697,0.0001208596,0.006995567,0.0002238642,0.0005592369,0.006670393,0.007883011,0.9671157,0.00004530497],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"commentary","genre_scores_codex":[0.02059117,0.1275248,0.00851542,0.04255141,0.03098702,0.0003357645,0.005395126,0.004207213,0.7598921],"genre_scores_gemma":[0.06413456,0.04954637,0.004257083,0.005405485,0.006723246,0.0001545166,0.007017747,0.0008708492,0.8618901],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.2917006,"threshold_uncertainty_score":0.9758357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1781261300932379,"score_gpt":0.4217005645802835,"score_spread":0.2435744344870457,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}