{"id":"W2011844493","doi":"10.1210/en.2006-1257","title":"3′5′-Cyclic Adenosine Monophosphate-Dependent Up-Regulation of Phosphodiesterase Type 3A in Porcine Cumulus Cells","year":2007,"lang":"en","type":"article","venue":"Endocrinology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Phosphodiesterase 3; Adenylyl cyclase; Internal medicine; Forskolin; PDE10A; Phosphodiesterase; IBMX; Endocrinology; Cyclic nucleotide phosphodiesterase; Activator (genetics); Cyclic nucleotide; Cycloheximide; Cyclic adenosine monophosphate; Protein kinase A; Adenosine; Biology; Chemistry; Stimulation; Cell biology; Receptor; Molecular biology; Kinase; Protein biosynthesis; Nucleotide; Biochemistry; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001552382,0.0003036154,0.000298491,0.0002869794,0.0001985053,0.0003531267,0.0001195399,0.0002311033,0.0009429227],"category_scores_gemma":[0.0001696044,0.0001611648,0.0005629191,0.0001562956,0.0003150796,0.0002103475,0.0002239226,0.0004911796,0.0003048039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004026157,"about_ca_system_score_gemma":0.0002847391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001418139,"about_ca_topic_score_gemma":0.001410382,"domain_scores_codex":[0.9998716,0.00002189065,0.00001228313,0.0000332588,0.00002628246,0.00003460727],"domain_scores_gemma":[0.9998517,0.00004084462,0.00003759168,0.00002327829,0.00001458208,0.00003212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006053503,0.00000798963,0.0001557034,0.00003224642,0.000002745111,0.00004766576,0.00001789474,0.00001343837,0.9990865,0.00003105936,0.00002349766,0.0005207228],"study_design_scores_gemma":[0.00002763219,0.0004219289,0.03566796,0.00001775583,0.00002662072,0.00035208,0.00007705062,0.00075672,0.9577902,0.0001192125,0.004730118,0.00001272551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809632,0.0082944,0.00441831,0.0003321576,0.0001643766,0.00008571278,0.0009749823,0.0001003474,0.004666447],"genre_scores_gemma":[0.9904121,0.002549957,0.003298262,0.0002843503,0.00007774396,0.00009557828,0.001060135,0.0000303612,0.002191592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001418139,"threshold_uncertainty_score":0.003154337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02227658189438325,"score_gpt":0.2990943687149871,"score_spread":0.2768177868206038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}