{"id":"W201185997","doi":"10.1139/o09-048","title":"A spectrum of gene regulatory phenomena at mammalian β-globin gene lociThis paper is one of a selection of papers published in this Special Issue, entitled 30th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.","year":2009,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chromatin; Biology; Enhancer; Gene; Gene silencing; Regulation of gene expression; Genetics; Psychological repression; ChIA-PET; Locus (genetics); Gene expression; Regulatory sequence; Function (biology); Promoter; Computational biology; Cell biology; Chromatin remodeling","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004654308,0.0006540711,0.001066402,0.001437119,0.0002701647,0.0006414675,0.0007137583,0.0008491304,0.002177882],"category_scores_gemma":[0.0004105097,0.0002428681,0.0002751734,0.001509976,0.0004845114,0.001038288,0.0004947923,0.0009657007,0.002148582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005729953,"about_ca_system_score_gemma":0.0007234225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006490023,"about_ca_topic_score_gemma":0.001157759,"domain_scores_codex":[0.9998493,0.0000188867,0.00001823912,0.00003454516,0.00006554776,0.00001344758],"domain_scores_gemma":[0.9998358,0.00006857733,0.00002326234,0.000007155838,0.00004862662,0.00001653426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004685763,0.00003089118,0.0001899307,0.008238107,0.00003360178,0.0003179316,0.00007083519,0.0002644744,0.00770152,0.004013162,0.0109345,0.9681582],"study_design_scores_gemma":[0.00001256149,0.00008065917,0.001027233,0.001218525,0.00005479817,0.002703566,0.00007029827,0.00007356024,0.003674417,0.001829004,0.989234,0.0000214622],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003106604,0.9965239,0.0004549845,0.0002334424,0.0001738927,0.000006994213,0.00002018661,0.00001390247,0.002262027],"genre_scores_gemma":[0.001172765,0.9969481,0.0004343627,0.0001574498,0.0001184814,0.000007257257,0.00003207094,0.000002254901,0.001127301],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002177882,"threshold_uncertainty_score":0.007285774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01578974996826115,"score_gpt":0.2654738290492225,"score_spread":0.2496840790809613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}