{"id":"W2011875119","doi":"10.4161/epi.6.4.14763","title":"Assessment of methylation level prediction accuracy in methyl-DNA immunoprecipitation and sodium bisulfite based microarray platforms","year":2011,"lang":"en","type":"article","venue":"Epigenetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Methylated DNA immunoprecipitation; Pyrosequencing; Bisulfite sequencing; Biology; DNA methylation; DNA microarray; Methylation; CpG site; Sodium bisulfite; Bisulfite; Computational biology; Illumina Methylation Assay; Microarray; Molecular biology; Genetics; DNA; Gene; Chemistry; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007273441,0.000190762,0.0002036585,0.000186893,0.00005764413,0.00001594091,0.0001245546,0.00023709,0.00001847163],"category_scores_gemma":[0.000137605,0.0001917829,0.00006692126,0.0001826971,0.00008670809,0.00001402504,0.00006114229,0.0001087857,0.000001133668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002798721,"about_ca_system_score_gemma":0.0001084073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008880014,"about_ca_topic_score_gemma":0.00009704903,"domain_scores_codex":[0.9985817,0.00009470418,0.0005497006,0.0003615037,0.0001976709,0.0002147032],"domain_scores_gemma":[0.9990629,0.00006842368,0.0002796387,0.0003462631,0.000176808,0.00006598297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004958797,0.0001068375,0.07553376,0.00003258013,0.00002837177,3.446882e-7,0.0003370253,0.0004883753,0.9156108,0.0001049925,0.000004741423,0.007702533],"study_design_scores_gemma":[0.0005820293,0.0002888451,0.4092942,0.00001545936,0.00002002294,3.078237e-7,0.00007811926,0.001232643,0.5876417,0.0004287696,0.0002953086,0.0001226527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9395678,0.00118896,0.05769792,0.00001659027,0.0002034079,0.0003336398,0.00005944201,0.000009097508,0.0009231493],"genre_scores_gemma":[0.9623398,0.0009485467,0.03621306,0.00002405132,0.00006005836,0.000029026,0.000296172,0.00002768353,0.00006162726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3337604,"threshold_uncertainty_score":0.7820678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04447762417336361,"score_gpt":0.2940678858911919,"score_spread":0.2495902617178283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}