{"id":"W2011899793","doi":"10.1002/etc.5620220507","title":"Development of a short-term reproductive endocrine bioassay using steroid hormone and vitellogenin end points in the estuarine mummichog (<i>Fundulus heteroclitus</i>)","year":2003,"lang":"en","type":"article","venue":"Environmental Toxicology and Chemistry","topic":"Reproductive biology and impacts on aquatic species","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"Fisheries and Oceans Canada; University of Guelph; University of New Brunswick","funders":"","keywords":"Vitellogenin; Internal medicine; Endocrinology; Testosterone (patch); Gonadosomatic Index; Biology; Endocrine disruptor; Endocrine system; Androgen; Sex steroid; Bioassay; Radioimmunoassay; Estrogen; Steroid hormone; Hormone; Steroid; Fish <Actinopterygii>; Medicine; Fecundity; Population; Ecology; Fishery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002561309,0.0004742698,0.0002977784,0.0003194685,0.000213242,0.0002462829,0.0003936557,0.0004025284,0.0008968829],"category_scores_gemma":[0.00020466,0.0002669221,0.00035462,0.0001526241,0.0002608469,0.0002087821,0.0003107115,0.0004341249,0.0002457605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000341805,"about_ca_system_score_gemma":0.0002882564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003028198,"about_ca_topic_score_gemma":0.008163176,"domain_scores_codex":[0.9998028,0.00002453184,0.00002792869,0.00005735407,0.00005888392,0.00002860638],"domain_scores_gemma":[0.999777,0.00003565429,0.00005718143,0.000027773,0.00005251939,0.00004985133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001296348,0.00003784016,0.001781719,0.00002644696,0.00000655271,0.0000160144,0.00002193064,0.00003787309,0.9963398,0.00000939623,0.00001133075,0.00158153],"study_design_scores_gemma":[0.00004042628,0.003905256,0.07341813,0.000008272574,0.00008904038,0.0001661171,0.00009959656,0.0005556825,0.920368,0.00002050221,0.001311931,0.00001710109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922159,0.0005105303,0.005392063,0.00003464608,0.00001489685,0.0002217685,0.0003452675,0.00006556838,0.001199368],"genre_scores_gemma":[0.9645136,0.0009223586,0.02606745,0.0001699832,0.00002748701,0.0008622162,0.001700338,0.00003764093,0.005698958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003028198,"threshold_uncertainty_score":0.006021142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01522241365402892,"score_gpt":0.244127302931704,"score_spread":0.228904889277675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}