{"id":"W2011899793","doi":"10.1002/etc.5620220507","title":"Development of a short-term reproductive endocrine bioassay using steroid hormone and vitellogenin end points in the estuarine mummichog (<i>Fundulus heteroclitus</i>)","year":2003,"lang":"en","type":"article","venue":"Environmental Toxicology and Chemistry","topic":"Reproductive biology and impacts on aquatic species","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"Fisheries and Oceans Canada; University of Guelph; University of New Brunswick","funders":"","keywords":"Vitellogenin; Internal medicine; Endocrinology; Testosterone (patch); Gonadosomatic Index; Biology; Endocrine disruptor; Endocrine system; Androgen; Sex steroid; Bioassay; Radioimmunoassay; Estrogen; Steroid hormone; Hormone; Steroid; Fish <Actinopterygii>; Medicine; Fecundity; Population; Ecology; Fishery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000357243,0.0002046921,0.0002141545,0.0000219677,0.00009960735,0.000007795204,0.0001129766,0.0001611909,0.00004564709],"category_scores_gemma":[0.0000853719,0.0001657918,0.00003288432,0.00004007169,0.0006624255,0.000008735818,0.0001275224,0.0001508029,8.970692e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003210347,"about_ca_system_score_gemma":0.00002646383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002116788,"about_ca_topic_score_gemma":0.000005115543,"domain_scores_codex":[0.998708,0.0001135262,0.0002976299,0.0005494947,0.00008252615,0.0002488961],"domain_scores_gemma":[0.9995009,0.00002495084,0.0000925325,0.0003225252,0.00000530129,0.00005384853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000118578,0.0002253222,0.0446434,0.00001371292,0.00006601875,0.000007936737,0.0003910196,0.000001515122,0.9535347,0.000005860544,0.00001277053,0.0009791799],"study_design_scores_gemma":[0.0005554297,0.0001524459,0.08245204,0.000005150646,0.00001894618,0.0003361297,0.0008549337,0.000002121799,0.9139451,0.00003732713,0.001476997,0.0001633782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966316,0.002738621,0.00005372758,0.00005428865,0.00003636485,0.0001862497,0.00000967649,0.000002699467,0.0002868192],"genre_scores_gemma":[0.9977425,0.0004621121,0.001424064,0.00009434443,0.00005371521,0.00001903767,0.00004380507,0.00001097509,0.0001494369],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03958958,"threshold_uncertainty_score":0.6760794,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01522241365402892,"score_gpt":0.244127302931704,"score_spread":0.228904889277675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}