{"id":"W2011939472","doi":"10.1111/j.1349-7006.2002.tb01288.x","title":"Hepatocyte Nuclear Factor (HNF)‐4α Induces Expression of Endothelial Fas Ligand (FasL) to Prevent Cancer Cell Transmigration: A Novel Defense Mechanism of Endothelium against Cancer Metastasis","year":2002,"lang":"en","type":"article","venue":"Japanese Journal of Cancer Research","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Fas ligand; Apoptosis; Extravasation; Cancer research; Biology; Endothelial stem cell; Cancer cell; Immune privilege; Cell biology; Cancer; Immunology; Programmed cell death; In vitro; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005428058,0.00019936,0.0003913017,0.0001983341,0.0001229816,0.00002694678,0.0003455528,0.000157534,0.0004111568],"category_scores_gemma":[0.00003927229,0.0001508899,0.0002400598,0.0002533045,0.0000801536,0.00003530855,0.00008589988,0.0002233082,0.000001436084],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001107857,"about_ca_system_score_gemma":0.0001934995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001086287,"about_ca_topic_score_gemma":0.0007860797,"domain_scores_codex":[0.9976348,0.0001689138,0.0006396737,0.0002926499,0.0009055174,0.0003583984],"domain_scores_gemma":[0.9982485,0.00003906633,0.0003930464,0.0002686738,0.0008233253,0.0002274508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006381302,0.0003243823,0.00007327834,0.0001048593,0.0001075155,0.000004100049,0.002774295,0.001152034,0.9888495,0.00003070556,0.00008338407,0.005857856],"study_design_scores_gemma":[0.001273914,0.0006895514,0.0001647725,0.0002015928,0.00004212817,0.00001030203,0.0007251529,0.0002551048,0.9936668,0.00002533268,0.002789079,0.0001563289],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994495,0.003810205,0.000481813,0.0002811466,0.0001831557,0.0004339017,0.0001952204,0.0000035431,0.0001160307],"genre_scores_gemma":[0.9878516,0.01063723,0.0006068475,0.00005896079,0.0003565483,0.00006277157,0.000003787183,0.00003873407,0.0003835524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006827029,"threshold_uncertainty_score":0.6153113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05047635074545704,"score_gpt":0.3278860926595225,"score_spread":0.2774097419140655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}