{"id":"W2011951513","doi":"10.1021/bi034335f","title":"G3 Domains of Aggrecan and PG-M/Versican Form Intermolecular Disulfide Bonds that Stabilize Cell−Matrix Interaction","year":2003,"lang":"en","type":"article","venue":"Biochemistry","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Aggrecan; Versican; Chemistry; Extracellular matrix; Proteoglycan; Intermolecular force; Chondrocyte; Cartilage; Biophysics; Biochemistry; Molecule; In vitro; Osteoarthritis; Organic chemistry; Anatomy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008499491,0.0004497533,0.00008876481,0.0001385153,0.000211336,0.0001562651,0.0001736825,0.0002182144,0.0005820767],"category_scores_gemma":[0.00007775141,0.00007025595,0.0002100897,0.0001164362,0.0002032029,0.0001576851,0.0002005518,0.0002555455,0.0001985309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002459926,"about_ca_system_score_gemma":0.0001768923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006714832,"about_ca_topic_score_gemma":0.0009556522,"domain_scores_codex":[0.9999272,0.00001419099,0.000003985308,0.00001536588,0.00001890273,0.00002038434],"domain_scores_gemma":[0.9999378,0.000006863376,0.00002849705,0.000005112685,0.000006014199,0.0000158468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003840655,0.00001264162,0.0007388407,0.00002428097,0.00001094358,0.0001308999,0.00002483744,0.00006811312,0.9973568,0.000173742,0.0000237949,0.001396832],"study_design_scores_gemma":[0.000009457272,0.0001482284,0.01255736,0.000006317747,0.0000177894,0.0007059113,0.00007074268,0.0007974466,0.9824265,0.0002242046,0.003030301,0.000005698439],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952267,0.001281015,0.002298223,0.00005057183,0.00001018625,0.00001173077,0.00007318254,0.00002611565,0.001022231],"genre_scores_gemma":[0.9967173,0.0004233764,0.001588907,0.00002985646,0.000002844356,0.000006122063,0.0001435809,0.000004566461,0.001083548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006714832,"threshold_uncertainty_score":0.001947224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009391266263335163,"score_gpt":0.2697293288996114,"score_spread":0.2603380626362762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}