{"id":"W2011966733","doi":"10.1016/j.antiviral.2008.10.005","title":"Differential induction of innate anti-viral responses by TLR ligands against Herpes simplex virus, type 2, infection in primary genital epithelium of women","year":2008,"lang":"en","type":"article","venue":"Antiviral Research","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Joseph’s Healthcare Hamilton; McMaster University","funders":"Canadian Institutes of Health Research; Health Canada; Ontario HIV Treatment Network; Hamilton Health Sciences; Canadian Foundation for AIDS Research; amfAR, The Foundation for AIDS Research","keywords":"TLR3; Innate immune system; Herpes simplex virus; Interferon; Biology; TLR4; Viral replication; Immunology; Virus; Microbicides for sexually transmitted diseases; Virology; Immune system; Toll-like receptor; Microbiology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001784594,0.0001663627,0.0002684035,0.0002612536,0.0003254405,0.0004230981,0.0001313589,0.0002520451,0.003385196],"category_scores_gemma":[0.0004345203,0.0001822611,0.0002622056,0.0001811585,0.0001989095,0.00020725,0.0003309106,0.0002919362,0.00045288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001944118,"about_ca_system_score_gemma":0.0002684918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005563651,"about_ca_topic_score_gemma":0.0006301744,"domain_scores_codex":[0.9997713,0.00005680889,0.00001557382,0.00003212676,0.00003155992,0.0000925266],"domain_scores_gemma":[0.9998825,0.00003192635,0.00001538141,0.00001433587,0.00002783357,0.00002803944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001506676,0.00006999512,0.01473074,0.0001502539,0.00001408876,0.0004633312,0.000429363,0.00002930229,0.9768018,0.0001131566,0.0001517915,0.005539526],"study_design_scores_gemma":[0.0001172962,0.00424109,0.4603768,0.0000997134,0.0001017772,0.004105685,0.004285668,0.0004223213,0.5180371,0.0003350847,0.007851987,0.00002555473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975058,0.0009758915,0.0001543615,0.00005319756,0.00002511227,0.00001722348,0.0001712948,0.000005928792,0.001091149],"genre_scores_gemma":[0.9967635,0.0009395556,0.0002091932,0.00007696442,0.0000192724,0.00003903202,0.0002739146,0.000004139115,0.001674511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003385196,"threshold_uncertainty_score":0.01132458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0553254321926722,"score_gpt":0.3577936452148949,"score_spread":0.3024682130222227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}