{"id":"W2011968755","doi":"10.1007/s00125-001-0743-z","title":"Mice with targeted gene disruptions or gene insertions for diabetes research: problems, pitfalls, and potential solutions","year":2002,"lang":"en","type":"review","venue":"Diabetologia","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Hospital for Sick Children; University of Toronto; Juvenile Diabetes Research Foundation International; National Cancer Institute; National Institutes of Health; American Diabetes Association","keywords":"Gene; Diabetes mellitus; Human physiology; Genetics; Biology; Medicine; Bioinformatics; Computational biology; Endocrinology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007122579,0.0006180929,0.002135836,0.0007317773,0.0008042988,0.0001104139,0.0002301869,0.0006188161,0.0003174903],"category_scores_gemma":[0.001063477,0.0004019078,0.0003669319,0.001115289,0.0006306259,0.0001297519,0.0001517843,0.0007849259,0.0001193273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001960701,"about_ca_system_score_gemma":0.0005470705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001241232,"about_ca_topic_score_gemma":0.00001035684,"domain_scores_codex":[0.996216,0.0003581911,0.0007945824,0.0009273472,0.0004468872,0.001256964],"domain_scores_gemma":[0.9971144,0.0009253242,0.0002807732,0.0006840933,0.0005234323,0.0004719571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006503986,0.008289514,0.003850985,0.1481317,0.01466396,0.0004809744,0.0007159717,0.00004860462,0.004460861,0.003178978,0.1657413,0.6497867],"study_design_scores_gemma":[0.002238834,0.001751034,0.0005271434,0.006214182,0.004989262,0.0002418843,0.0000544972,0.0003984914,0.00008517279,0.0001230044,0.9825354,0.0008410843],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003295884,0.990002,0.0004114149,0.0004781359,0.000251051,0.003989387,0.0009582601,0.0002518657,0.0003620386],"genre_scores_gemma":[0.000936303,0.9823986,0.005659949,0.000171357,0.0003747715,0.003413249,0.002518321,0.0001337132,0.004393762],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8167941,"threshold_uncertainty_score":0.9998433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1874943489984023,"score_gpt":0.3625501228292478,"score_spread":0.1750557738308454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}