{"id":"W2011998179","doi":"10.1161/circulationaha.114.014634","title":"Making Sense of Genome-Wide Association Studies","year":2014,"lang":"en","type":"letter","venue":"Circulation","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Genome-wide association study; Genetics; Gene; Genome; Genetic association; Genealogy; Biology; Medicine; Single-nucleotide polymorphism; Genotype; History","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.05450463,0.001249967,0.00462623,0.002537606,0.003925396,0.008703951,0.005496336,0.06653943,0.004216088],"category_scores_gemma":[0.246079,0.001616371,0.0019143,0.001885946,0.01976062,0.01372345,0.004947925,0.08487758,0.003179495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003738443,"about_ca_system_score_gemma":0.002951928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003240008,"about_ca_topic_score_gemma":0.005867655,"domain_scores_codex":[0.9578717,0.02331274,0.005000983,0.00423765,0.008628765,0.0009481916],"domain_scores_gemma":[0.707817,0.2436766,0.009093334,0.01048088,0.02047943,0.008452727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002919121,0.0001077552,0.005535657,0.0003506488,0.0003904191,0.003384801,0.0004972202,0.000389535,0.0003062645,0.01604822,0.9259495,0.04674806],"study_design_scores_gemma":[0.0008573172,0.0002179351,0.008003606,0.002779563,0.0006101808,0.008168192,0.001631271,0.00305171,0.0006861724,0.2502857,0.7231998,0.0005085468],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002144395,0.00285405,0.0005728552,0.981362,0.01420057,0.000005976978,0.00003477297,0.0000184674,0.0007369191],"genre_scores_gemma":[0.004307671,0.002077555,0.001185707,0.8649404,0.1266183,0.00002927343,0.00002343163,0.00002104035,0.000796649],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.06653943,"threshold_uncertainty_score":0.2882514,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0458108957123881,"score_gpt":0.3034280617993195,"score_spread":0.2576171660869314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}