{"id":"W2012016148","doi":"10.1128/aac.00043-09","title":"The Chromosomal Toxin Gene <i>yafQ</i> Is a Determinant of Multidrug Tolerance for <i>Escherichia coli</i> Growing in a Biofilm","year":2009,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":179,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Multidrug tolerance; Microbiology; Biofilm; Biology; Antitoxin; Escherichia coli; Tobramycin; Antibiotics; Population; Plasmid; Toxin; Gentamicin; Gene; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001277395,0.000185196,0.0002263392,0.00001842843,0.000114127,0.00003785838,0.0002098662,0.0001219749,0.000003552359],"category_scores_gemma":[0.000009614429,0.0001450239,0.0001037392,0.00007761967,0.0001150301,0.00001027938,0.00002647911,0.00005501175,4.257603e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008930128,"about_ca_system_score_gemma":0.00003549245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002105497,"about_ca_topic_score_gemma":0.0000183333,"domain_scores_codex":[0.9989716,0.00002421623,0.000310477,0.0003251519,0.00006694387,0.0003016415],"domain_scores_gemma":[0.9995269,0.00001327285,0.0001317637,0.0002468871,0.00004123632,0.00003991704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003978634,0.0001021202,0.007349861,0.00002353214,0.00002396109,0.000002015757,0.0001250459,0.000002434661,0.9815909,0.000009719969,0.003434958,0.006937563],"study_design_scores_gemma":[0.001668288,0.0002102697,0.03840232,0.00005860504,0.000008255601,0.000006567662,0.00002343239,0.0001258547,0.9306304,0.00002073887,0.0286508,0.0001944347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978191,0.0001817466,0.0002934369,0.001125576,0.0001017415,0.0003849715,0.00004284378,0.000005292974,0.00004524164],"genre_scores_gemma":[0.9873572,0.002260008,0.002328707,0.007683048,0.0001172281,0.000006077748,0.00002015932,0.00002184295,0.0002057405],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05096049,"threshold_uncertainty_score":0.5913904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006957293556363749,"score_gpt":0.2428303621809828,"score_spread":0.2358730686246191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}