{"id":"W2012016148","doi":"10.1128/aac.00043-09","title":"The Chromosomal Toxin Gene <i>yafQ</i> Is a Determinant of Multidrug Tolerance for <i>Escherichia coli</i> Growing in a Biofilm","year":2009,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":179,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Multidrug tolerance; Microbiology; Biofilm; Biology; Antitoxin; Escherichia coli; Tobramycin; Antibiotics; Population; Plasmid; Toxin; Gentamicin; Gene; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001606712,0.0002826392,0.0002890807,0.0001864768,0.0001798607,0.0004299007,0.0002328386,0.0003483948,0.0005666591],"category_scores_gemma":[0.0002993317,0.0001617055,0.0002212997,0.0001536444,0.0002615133,0.000167218,0.0003317366,0.0005480241,0.0003322991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000455189,"about_ca_system_score_gemma":0.0003151306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001428521,"about_ca_topic_score_gemma":0.001435349,"domain_scores_codex":[0.9997686,0.00003155634,0.00002081143,0.00003807547,0.00008773771,0.00005327879],"domain_scores_gemma":[0.9997744,0.0000480963,0.000073793,0.0000244502,0.00003654851,0.00004269484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001195674,0.000005488878,0.0003182872,0.000007440155,0.000001268057,0.00002306487,0.00000425763,0.00001920127,0.9993105,0.0000239593,0.000007605778,0.0002669912],"study_design_scores_gemma":[0.000005522466,0.0000999517,0.02108367,0.000008524331,0.000008294868,0.0006035495,0.00005442464,0.0007665306,0.9763262,0.00003114009,0.001005124,0.000007134562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967203,0.0003233142,0.002271676,0.0000915057,0.000006979983,0.00001161646,0.0001647616,0.00003268847,0.0003771333],"genre_scores_gemma":[0.9967685,0.0001447216,0.002027117,0.00004143396,0.000003014311,0.00001290605,0.0003327875,0.00001736136,0.0006522879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001428521,"threshold_uncertainty_score":0.003302634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006957293556363749,"score_gpt":0.2428303621809828,"score_spread":0.2358730686246191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}