{"id":"W2012022457","doi":"10.1002/ijc.21464","title":"Mammalian lignans enterolactone and enterodiol, alone and in combination with the isoflavone genistein, do not promote the growth of MCF‐7 xenografts in ovariectomized athymic nude mice","year":2005,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Phytoestrogen effects and research","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Tekes","keywords":"Enterolactone; Ovariectomized rat; Phytoestrogens; Apoptosis; Internal medicine; Endocrinology; Genistein; Cell growth; Isoflavones; Cancer research; Biology; Medicine; Estrogen; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006550252,0.0001028091,0.0002495406,0.000201597,0.00002691196,0.00004029758,0.0001813787,0.000039538,0.00002021588],"category_scores_gemma":[0.00004401557,0.00005201252,0.00004643398,0.000123476,0.0001620955,0.0001518095,0.00004561867,0.0003324898,4.097202e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001268544,"about_ca_system_score_gemma":0.00009988219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002757297,"about_ca_topic_score_gemma":0.0007899796,"domain_scores_codex":[0.998764,0.0001008913,0.0003433899,0.0001133378,0.0005391776,0.000139244],"domain_scores_gemma":[0.999191,0.0001027391,0.0002470338,0.00007427358,0.0003294627,0.00005541964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.03260114,0.001476114,0.3520227,0.0002100935,0.001227051,0.0004004673,0.006811512,0.0001291008,0.5733783,0.0003123434,0.0004316009,0.03099964],"study_design_scores_gemma":[0.02835362,0.001373902,0.8384378,0.001280811,0.0001519986,0.0008895916,0.00024459,0.0009682495,0.1265425,0.0001591773,0.001444702,0.0001531239],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9759328,0.002134329,0.00008307044,0.02141111,0.00009500483,0.0002953514,0.000009188196,0.000001821309,0.00003734815],"genre_scores_gemma":[0.998357,0.0008049016,0.000143993,0.0004031686,0.0002116372,0.0000135975,0.000001901056,0.0000109067,0.00005288708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4864151,"threshold_uncertainty_score":0.2121009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009013026082376183,"score_gpt":0.2958698406954263,"score_spread":0.2868568146130501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}