{"id":"W2012025493","doi":"10.1038/nsmb.1911","title":"The program for processing newly synthesized histones H3.1 and H4","year":2010,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":270,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Metropolitan University; University of Toronto","funders":"National Institute of General Medical Sciences; Howard Hughes Medical Institute","keywords":"Histone; Karyopherin; Histone code; Chromatin; Histone methyltransferase; Histone H4; Histone H1; Histone-modifying enzymes; Biology; Acetylation; Cell biology; Histone H2A; Histone octamer; Histone H3; Cytoplasm; Nucleosome; Nuclear transport; Biochemistry; Cell nucleus; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005879321,0.0007801905,0.0004638139,0.0005323213,0.0009212646,0.001165811,0.0008445591,0.0005465679,0.00553501],"category_scores_gemma":[0.0007351639,0.0005094655,0.0007732405,0.0003384546,0.0005189476,0.0006681395,0.001297154,0.00173629,0.004306978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001085096,"about_ca_system_score_gemma":0.001488485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002119299,"about_ca_topic_score_gemma":0.002033436,"domain_scores_codex":[0.9996541,0.0000305482,0.00001262163,0.000128934,0.00008103299,0.0000927718],"domain_scores_gemma":[0.999503,0.0000778268,0.00005227068,0.0001174044,0.0001103514,0.0001391131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007657318,0.0001488533,0.001822494,0.0001614038,0.00002835061,0.0002131269,0.0001314309,0.0003608074,0.9218323,0.01193979,0.006626139,0.05596954],"study_design_scores_gemma":[0.00008634746,0.0003418111,0.00619379,0.00002005712,0.00003848205,0.0003821105,0.00007036501,0.002907264,0.9342909,0.00230211,0.05333421,0.00003255183],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6541378,0.003799047,0.2850246,0.002348453,0.001952069,0.0009110434,0.004068754,0.01121404,0.03654411],"genre_scores_gemma":[0.714766,0.001560605,0.1770022,0.001055896,0.0002668434,0.0007354537,0.01040382,0.002403282,0.09180588],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00553501,"threshold_uncertainty_score":0.01851642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.001901704774819516,"score_gpt":0.277335661270579,"score_spread":0.2754339564957595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}