{"id":"W2012035884","doi":"10.4236/ajac.2011.23043","title":"A Validated Liquid Chromatography-Mass Spectrometry Method for the Detection and Quantification of Oxidative Metabolites of 2,2',4,4'-Tetrabromodiphenyl Ether in Rat Hepatic Microsomes","year":2011,"lang":"en","type":"article","venue":"American Journal of Analytical Chemistry","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of British Columbia","funders":"","keywords":"Chromatography; Chemistry; Mass spectrometry; Liquid chromatography–mass spectrometry; Ether; Oxidative phosphorylation; Microsome; Organic chemistry; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007842564,0.0001354843,0.0004447019,0.00007961696,0.00002721515,0.000008456581,0.0002478752,0.00004870324,0.0002932141],"category_scores_gemma":[0.0004375278,0.00009390602,0.0001493714,0.0008247964,0.0007697091,0.0001222289,0.00003122432,0.0001791064,6.178762e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006331418,"about_ca_system_score_gemma":0.00002958515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001247988,"about_ca_topic_score_gemma":0.00000644898,"domain_scores_codex":[0.9987136,0.0001017957,0.0005808233,0.0001649039,0.0002455275,0.0001933146],"domain_scores_gemma":[0.9984713,0.0004658871,0.0007418572,0.0002020622,0.0000201474,0.00009875501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002909249,0.00009952232,0.003516668,0.00001525472,0.0001370282,0.000001256345,0.0004082293,0.000008367513,0.9902843,0.000006737233,0.000002144588,0.005229563],"study_design_scores_gemma":[0.0003240416,0.000410728,0.02917447,0.00002522207,0.0001888429,0.00004051405,0.0009507708,0.001076249,0.9673641,0.0003398144,0.00001003032,0.00009517149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.919583,0.0001905779,0.0798918,0.00006915649,0.00001858036,0.00008894256,0.00002088353,0.000003713021,0.0001332987],"genre_scores_gemma":[0.9688836,0.00007089915,0.03099083,0.00001484222,0.00001431784,0.000001333622,2.454529e-7,0.0000126951,0.00001127505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04930051,"threshold_uncertainty_score":0.3829376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01462962589227799,"score_gpt":0.2710971762604715,"score_spread":0.2564675503681935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}