{"id":"W2012040708","doi":"10.1016/j.cbpa.2010.08.004","title":"Ammonia uptake in Manduca sexta midgut is mediated by an amiloride sensitive cation/proton exchanger: Transport studies and mRNA expression analysis of NHE7, 9, NHE8, and V-ATPase (subunit D)","year":2010,"lang":"en","type":"article","venue":"Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Amiloride; Manduca sexta; Epithelial sodium channel; Midgut; Intracellular pH; Ussing chamber; Ion transporter; Biochemistry; Biology; Sodium–hydrogen antiporter; Proton transport; Manduca; Biophysics; Chemistry; Apical membrane; Sodium; Extracellular; Secretion; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006568237,0.0001889015,0.0001816679,0.0001839922,0.0003075821,0.0002435118,0.0001733778,0.0002191255,0.0006564342],"category_scores_gemma":[0.00006522673,0.0002404385,0.0002334942,0.00007452304,0.0001750881,0.0003206417,0.0001915971,0.0003384821,0.0002293391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000448406,"about_ca_system_score_gemma":0.0001750662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002037039,"about_ca_topic_score_gemma":0.004360997,"domain_scores_codex":[0.9999502,0.000003102382,0.000003386082,0.0000184412,0.00001139252,0.00001354171],"domain_scores_gemma":[0.9999253,0.00001123914,0.0000195732,0.000007252432,0.00001762172,0.00001900591],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005719039,0.000002616127,0.0003117608,0.00001362591,0.000002232538,0.00001552762,0.00001287085,0.000007147732,0.9991854,0.0000469474,0.000008258464,0.0003364382],"study_design_scores_gemma":[0.00001894331,0.0001908895,0.07783484,0.00001097642,0.00003849524,0.0002886612,0.0001305231,0.001170628,0.918184,0.0001246731,0.001998732,0.00000864459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976977,0.0006529421,0.0008600403,0.00005370284,0.00001018301,0.000005057673,0.0001202237,0.00002288015,0.000577328],"genre_scores_gemma":[0.9944248,0.0004674835,0.001175817,0.00006443723,0.00001235743,0.00001839665,0.0005224419,0.00002296976,0.003291283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002037039,"threshold_uncertainty_score":0.004050374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02854378107510867,"score_gpt":0.2949522941416199,"score_spread":0.2664085130665112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}