{"id":"W2012080977","doi":"10.1038/nrm2821","title":"Regulation of cell signalling by uPAR","year":2009,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":968,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Urokinase receptor; Vitronectin; Cell biology; Integrin; Receptor; Plasminogen activator; Signal transduction; Extracellular matrix; Chemistry; Intracellular; Extracellular; Cell migration; SuPAR; Urokinase; Biology; Cell; Biochemistry; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006926232,0.001465793,0.001934162,0.001410611,0.0003164372,0.001677984,0.001357085,0.001355501,0.002605635],"category_scores_gemma":[0.0004655387,0.0005238194,0.0003951489,0.001569512,0.0009282079,0.001781391,0.001064776,0.00279548,0.004278456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009396314,"about_ca_system_score_gemma":0.0007477571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004970126,"about_ca_topic_score_gemma":0.0008763674,"domain_scores_codex":[0.999746,0.00002403544,0.0000304696,0.0000534446,0.0001127106,0.00003327654],"domain_scores_gemma":[0.9997732,0.0000745815,0.00003597137,0.00001263609,0.00007080635,0.00003276571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001909347,0.00007293548,0.0001335962,0.006879331,0.00007863263,0.0004073937,0.00003668486,0.0006723683,0.01957243,0.00698468,0.03220333,0.9327676],"study_design_scores_gemma":[0.00005633037,0.00007171668,0.001025081,0.001172896,0.0001019525,0.001361161,0.00006007448,0.0003018046,0.007194816,0.005116174,0.9835012,0.00003688709],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003439951,0.9947209,0.001126647,0.0005689076,0.0006940281,0.00001144957,0.00004861725,0.00004502617,0.002440436],"genre_scores_gemma":[0.001561767,0.9952304,0.0005246826,0.0004218127,0.0003891227,0.00001530415,0.00007814677,0.000004425563,0.00177425],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002605635,"threshold_uncertainty_score":0.008716762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01178546432210058,"score_gpt":0.2878824870949926,"score_spread":0.276097022772892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}