{"id":"W2012121835","doi":"10.1016/j.micpath.2009.10.003","title":"A role for sigma factor B in the emergence of Staphylococcus aureus small-colony variants and elevated biofilm production resulting from an exposure to aminoglycosides","year":2009,"lang":"en","type":"article","venue":"Microbial Pathogenesis","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Cystic Fibrosis Foundation","keywords":"Staphylococcus aureus; Microbiology; Biofilm; Sigma factor; Aminoglycoside; Gentamicin; Biology; Mutant; Gene; Antibiotics; Phenotype; Bacteria; Gene expression; Genetics; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004866089,0.0003230502,0.0005325596,0.0002378525,0.0001578659,0.00004093691,0.0002828916,0.000204185,0.00001896432],"category_scores_gemma":[0.000656296,0.000265341,0.0001184968,0.0006525333,0.00008151623,0.0001156073,0.00004038133,0.000159555,0.000002417079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005347748,"about_ca_system_score_gemma":0.0001128506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004430044,"about_ca_topic_score_gemma":0.00107748,"domain_scores_codex":[0.9976887,0.0001769681,0.0006902358,0.0007544246,0.0002031778,0.0004865079],"domain_scores_gemma":[0.9985924,0.0001290841,0.0002487337,0.0006139108,0.0002822914,0.0001335151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00169504,0.0003622886,0.01152763,0.000063014,0.00003442857,0.00001824906,0.00296918,0.00008727801,0.9731494,0.00000703286,0.0003810979,0.009705413],"study_design_scores_gemma":[0.0009817205,0.000913935,0.4659777,0.0001819858,0.00009103119,0.000005818325,0.0008628727,0.00004430755,0.5304026,0.00005271287,0.0002414909,0.0002438742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948599,0.0003840775,0.0006204821,0.0009178238,0.0001694628,0.002281267,0.000703687,0.00004970634,0.0000136273],"genre_scores_gemma":[0.9906744,0.00004382912,0.008167934,0.0005692026,0.0003014355,0.00006529873,0.00009574137,0.00003641053,0.0000457479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.45445,"threshold_uncertainty_score":0.9999799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02399271766689053,"score_gpt":0.2765311150613052,"score_spread":0.2525383973944146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}