{"id":"W2012132820","doi":"10.1128/iai.01527-07","title":"Immunization with a Toll-Like Receptor 7 and/or 8 Agonist Vaccine Adjuvant Increases Protective Immunity against<i>Leishmania major</i>in BALB/c Mice","year":2008,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Adjuvant; Imiquimod; Vaccination; Immunology; Leishmania major; TLR7; Immune system; Antigen; Immunization; Immunity; Toll-like receptor; Biology; Leishmania; Medicine; Virology; Innate immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002795607,0.000758515,0.0005320028,0.00062364,0.0001491724,0.0003526492,0.0002239867,0.0004585111,0.001519745],"category_scores_gemma":[0.0002181235,0.0002689381,0.000305505,0.0001575291,0.0003629707,0.0003648672,0.0001490879,0.001349109,0.0004464311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003176768,"about_ca_system_score_gemma":0.0002924658,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004705308,"about_ca_topic_score_gemma":0.0007323756,"domain_scores_codex":[0.9997277,0.00004835583,0.00002271172,0.0000646769,0.00004789111,0.00008862113],"domain_scores_gemma":[0.9997043,0.00004292897,0.00009434997,0.00002667539,0.00003009544,0.0001014748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005722066,0.0002901603,0.000136081,0.0000572352,0.000005887623,0.00003107515,0.00001343389,0.00003636683,0.9974833,0.00003496336,0.00006054554,0.001278642],"study_design_scores_gemma":[0.0002814853,0.008247369,0.004869244,0.00003855851,0.00005966628,0.0003731238,0.00004316314,0.0006392226,0.9839372,0.00006336813,0.001437099,0.00001047477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959219,0.001262607,0.0008015616,0.0001893151,0.00005210029,0.00004750857,0.0002482948,0.0001646725,0.001311991],"genre_scores_gemma":[0.9927498,0.001152634,0.00232785,0.000163337,0.00004253766,0.00004984437,0.0004993489,0.00004536893,0.002969446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001519745,"threshold_uncertainty_score":0.005084038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02050207259815897,"score_gpt":0.2704540498039449,"score_spread":0.249951977205786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}