{"id":"W2012157443","doi":"10.1002/cne.22430","title":"Progranulin expression in the developing and adult murine brain","year":2010,"lang":"en","type":"article","venue":"The Journal of Comparative Neurology","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":157,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia Hospital; Children's & Women's Health Centre of British Columbia; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biology; Microglia; Frontotemporal lobar degeneration; Neuroscience; Genetically modified mouse; Central nervous system; Transgene; Gene expression; Gene; Pathology; Frontotemporal dementia; Genetics; Immunology; Inflammation; Disease; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017282,0.0003152469,0.0001630901,0.0009409977,0.000215806,0.0004090973,0.000281728,0.0003685991,0.0008603283],"category_scores_gemma":[0.0001380703,0.0002491489,0.0001911039,0.0001286581,0.0003355257,0.0002847896,0.000251361,0.0006002408,0.0003922304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006507675,"about_ca_system_score_gemma":0.0002530864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001212113,"about_ca_topic_score_gemma":0.002546168,"domain_scores_codex":[0.9998471,0.00001673128,0.00001553207,0.00004611441,0.00004330747,0.00003135635],"domain_scores_gemma":[0.9998502,0.000018449,0.00004937179,0.00001033425,0.0000183625,0.00005339138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001365882,0.00001965671,0.0003692521,0.00003930994,0.000007124797,0.0002009053,0.00005240504,0.00006676849,0.9970722,0.0002378488,0.00004233493,0.001755487],"study_design_scores_gemma":[0.00005571486,0.0008950445,0.03195827,0.00008961697,0.00007493544,0.002189368,0.0001557307,0.000880523,0.9541645,0.0005484912,0.008961843,0.00002589312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985524,0.006572584,0.002711269,0.00009764099,0.00003118253,0.00003715667,0.001324355,0.0001446146,0.003557142],"genre_scores_gemma":[0.9754548,0.004386265,0.009669202,0.0001193801,0.0000138102,0.0000978254,0.001748255,0.0001066636,0.00840365],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001212113,"threshold_uncertainty_score":0.004721642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04869903618850738,"score_gpt":0.3617227064702085,"score_spread":0.3130236702817011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}