{"id":"W2012177852","doi":"10.1021/bm501109p","title":"Construction and Characterization of Kilobasepair Densely Labeled Peptide-DNA","year":2014,"lang":"en","type":"article","venue":"Biomacromolecules","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Vetenskapsrådet; Human Frontier Science Program","keywords":"Alkyne; Peptide; DNA; Click chemistry; Modular design; Orthogonality; Biocompatible material; Characterization (materials science); Chemistry; Nanotechnology; Cleavage (geology); Chemical biology; Combinatorial chemistry; Persistence length; Materials science; Computer science; Biochemistry; Molecule; Mathematics; Engineering; Biomedical engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001098935,0.0001185778,0.0001404322,0.00005408902,0.00005165635,0.00001297496,0.00005814626,0.0001072325,0.000001048363],"category_scores_gemma":[0.00004920689,0.0001078597,0.00005502361,0.00009372344,0.000183269,0.000003518093,0.00004557164,0.00002455731,8.56595e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004255987,"about_ca_system_score_gemma":0.00001219136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004596545,"about_ca_topic_score_gemma":0.000006604064,"domain_scores_codex":[0.9993135,0.00006142368,0.0001819091,0.0002461253,0.00008006873,0.0001170057],"domain_scores_gemma":[0.9995437,0.000006071656,0.000133859,0.0001764182,0.0000968478,0.00004316388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003074068,0.00002079048,0.001298028,0.00001548405,0.00002824974,7.969074e-7,0.000005267374,4.120368e-8,0.9891229,0.0002607278,0.00004071775,0.009176305],"study_design_scores_gemma":[0.000191075,0.0001933575,0.003568858,0.00001774269,0.00002694169,0.00004272701,0.000009810859,0.00004152053,0.9920494,0.0001108288,0.003616522,0.000131236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902068,0.00003985491,0.009341977,0.00006720812,0.00003156222,0.00007271285,0.00002927161,0.0000366376,0.0001739399],"genre_scores_gemma":[0.9884221,0.0001015987,0.01103795,0.00007780089,0.00006337736,0.000002960904,0.0002192913,0.00001240159,0.00006254288],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009045069,"threshold_uncertainty_score":0.439839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004671668122629704,"score_gpt":0.224831454867515,"score_spread":0.2201597867448853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}