{"id":"W2012254521","doi":"10.1038/modpathol.2013.144","title":"ARID1A loss correlates with mismatch repair deficiency and intact p53 expression in high-grade endometrial carcinomas","year":2013,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":133,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital; Mount Sinai Hospital; Princess Margaret Cancer Centre; University of British Columbia; University Health Network","funders":"National Cancer Institute","keywords":"ARID1A; Serous fluid; Clear cell; Clear cell carcinoma; Medicine; Immunohistochemistry; Serous carcinoma; Microsatellite instability; Carcinoma; Endometrial cancer; Pathology; DNA mismatch repair; Cancer research; Internal medicine; Cancer; Oncology; Biology; Mutation; Gene; Ovarian cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003833806,0.0002025925,0.0002656177,0.001335911,0.000265,0.0005958448,0.0003569761,0.0003188104,0.001459065],"category_scores_gemma":[0.001172998,0.0003521924,0.0001959871,0.0006845995,0.0005102285,0.0003157131,0.0004119818,0.0002870442,0.000347758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001600455,"about_ca_system_score_gemma":0.0001656956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003550277,"about_ca_topic_score_gemma":0.0003270177,"domain_scores_codex":[0.9997564,0.00004874309,0.00004991414,0.00004354411,0.00005655258,0.00004480423],"domain_scores_gemma":[0.9988021,0.000233516,0.0005263088,0.0001187863,0.00009196709,0.0002274541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002718943,0.00008526862,0.690927,0.00008423013,0.0001373958,0.0030921,0.000184948,0.0001840901,0.2963988,0.0002105146,0.0001241567,0.005852697],"study_design_scores_gemma":[0.00002097564,0.0001302949,0.9660544,0.000005868326,0.00006190966,0.007540554,0.0002804364,0.0005141078,0.02468397,0.0001746549,0.0005239301,0.000008950843],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989721,0.0004396277,0.0002458958,0.00001919718,0.000002873936,0.000002916806,0.0000726651,0.000008444745,0.0002363645],"genre_scores_gemma":[0.9995535,0.0001265131,0.0001097313,0.000006246266,0.000004544811,0.000003195,0.00006887469,0.000002221659,0.0001251557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001459065,"threshold_uncertainty_score":0.004881024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008354661122166,"score_gpt":0.2217707474362296,"score_spread":0.2134160863140636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}