{"id":"W2012323944","doi":"10.1016/j.jconrel.2014.03.008","title":"Effect of initial pBMP-9 loading and collagen concentration on the kinetics of peptide release and a mathematical model of the delivery system","year":2014,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Collagen: Extraction and Characterization","field":"Materials Science","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Peptide; Chemistry; Kinetics; Biophysics; Type I collagen; Drug delivery; Collagen fiber; Bone morphogenetic protein 2; Bone morphogenetic protein; Biochemistry; Anatomy; In vitro; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001143625,0.000103897,0.0004879459,0.00004809399,0.00006027302,0.00002998871,0.0001090203,0.00005992525,0.00002778417],"category_scores_gemma":[0.001030475,0.00005392486,0.0001125299,0.00007264723,0.0001230814,0.00009231659,0.00002372648,0.00007527332,7.547327e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000265863,"about_ca_system_score_gemma":0.00005822785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002421792,"about_ca_topic_score_gemma":8.593072e-7,"domain_scores_codex":[0.9981881,0.0005733675,0.0007162559,0.00007894679,0.0003552892,0.00008797641],"domain_scores_gemma":[0.9972807,0.001054365,0.001189242,0.0001416109,0.0002678566,0.00006619318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003826469,0.00006452583,0.00004160532,0.0002628374,0.00003003014,0.000001804283,0.000266159,0.001610453,0.9915856,0.001777316,0.00003089302,0.0005022843],"study_design_scores_gemma":[0.008276954,0.001158919,0.0003846966,0.0007158145,0.000393696,0.00006732334,0.0002135965,0.2852864,0.7032348,0.0001686961,0.00001375612,0.00008535987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951664,0.00007090266,0.003618516,0.0001986709,0.0001118213,0.0004196762,0.00001053797,0.000003566885,0.0003999525],"genre_scores_gemma":[0.9997373,0.00003452124,0.00007222213,0.00004462653,0.00006366528,0.000004280881,2.891348e-7,0.000007449284,0.00003566712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2883509,"threshold_uncertainty_score":0.2198992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008749597190707921,"score_gpt":0.2403167388652705,"score_spread":0.2315671416745626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}