{"id":"W2012387946","doi":"10.1038/nbt1145","title":"A human β-cell line for transplantation therapy to control type 1 diabetes","year":2005,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":134,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Japan Society for the Promotion of Science; National Institutes of Health; University of Alberta; Northwestern University","keywords":"Transplantation; Telomerase reverse transcriptase; Transfection; Viral vector; Biology; Cell culture; Genetic enhancement; Molecular biology; Cell biology; Virology; Internal medicine; Medicine; Telomerase; Gene; Recombinant DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004845841,0.000475694,0.0004137904,0.0004166891,0.0002551159,0.0006211927,0.0004260025,0.0004796935,0.004614421],"category_scores_gemma":[0.0002350329,0.000172724,0.0004460193,0.0004215152,0.0002133934,0.0003167714,0.0002119894,0.002177884,0.002454851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001250874,"about_ca_system_score_gemma":0.0002932943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002389216,"about_ca_topic_score_gemma":0.0002357714,"domain_scores_codex":[0.9998195,0.00004324936,0.000023635,0.00003218657,0.00005864331,0.00002292503],"domain_scores_gemma":[0.9998317,0.00005221696,0.00001426023,0.00004408719,0.00002529103,0.00003241746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003983144,0.0002005602,0.0001828003,0.00007916013,0.00001747442,0.0001408523,0.00003240386,0.0001103346,0.9890198,0.0005461492,0.001113837,0.008158257],"study_design_scores_gemma":[0.0002455386,0.001091876,0.001430687,0.0000458054,0.0001439367,0.001278122,0.00003678041,0.0009974024,0.954634,0.0003520019,0.03973104,0.00001272466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.866398,0.01868805,0.07128786,0.002337701,0.003588105,0.0008286604,0.01030279,0.001370405,0.02519849],"genre_scores_gemma":[0.8950098,0.01734785,0.04807766,0.001035883,0.0004397509,0.0004827655,0.01501627,0.0003940845,0.02219584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004614421,"threshold_uncertainty_score":0.01543677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009037988973153149,"score_gpt":0.2776895964240056,"score_spread":0.2686516074508524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}