{"id":"W2012387946","doi":"10.1038/nbt1145","title":"A human β-cell line for transplantation therapy to control type 1 diabetes","year":2005,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":134,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Japan Society for the Promotion of Science; National Institutes of Health; University of Alberta; Northwestern University","keywords":"Transplantation; Telomerase reverse transcriptase; Transfection; Viral vector; Biology; Cell culture; Genetic enhancement; Molecular biology; Cell biology; Virology; Internal medicine; Medicine; Telomerase; Gene; Recombinant DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009063806,0.000115474,0.0002367649,0.0001977307,0.00005286513,0.000005387411,0.00006952846,0.0007658559,0.0000890754],"category_scores_gemma":[0.0001001253,0.00009137889,0.00005825755,0.0002056769,0.00003614879,0.00002169735,0.000003933837,0.0003186477,0.00005008751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003056627,"about_ca_system_score_gemma":0.00002495548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001617208,"about_ca_topic_score_gemma":0.0000036845,"domain_scores_codex":[0.9993414,0.000009910741,0.0001418644,0.0002152132,0.00007754558,0.0002140872],"domain_scores_gemma":[0.9995573,0.00005862325,0.00003649271,0.0001970862,0.00008863669,0.00006190203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003525865,0.0001503529,0.000540512,0.00004208814,0.00004780023,0.000001505274,0.00003547407,0.000007204462,0.9697211,0.001203335,0.005656051,0.02224197],"study_design_scores_gemma":[0.005527368,0.001773427,0.001418676,0.00002288107,0.00006998902,0.000004202222,0.00001422855,0.0002156805,0.8457048,0.0001389765,0.1449959,0.0001138675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9714003,0.002551748,0.0007076561,0.02327017,0.0002038372,0.0007459936,0.00002493861,0.0002837454,0.0008116602],"genre_scores_gemma":[0.9851633,0.0001121181,0.003396966,0.01004202,0.0002825905,0.00005720586,0.00005340608,0.00001782442,0.000874575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1393398,"threshold_uncertainty_score":0.5906982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009037988973153149,"score_gpt":0.2776895964240056,"score_spread":0.2686516074508524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}