{"id":"W2012439219","doi":"10.1161/circulationaha.113.002275","title":"Innate Immune Interleukin-1 Receptor–Associated Kinase 4 Exacerbates Viral Myocarditis by Reducing CCR5 <sup>+</sup> CD11b <sup>+</sup> Monocyte Migration and Impairing Interferon Production","year":2013,"lang":"en","type":"article","venue":"Circulation","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Interferon; Immunology; Viral Myocarditis; Myocarditis; Innate immune system; Medicine; Immune system; Biology; Virus; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001677634,0.0004963862,0.0003070523,0.0001649732,0.0001071705,0.000274706,0.0001914142,0.0002291885,0.001539839],"category_scores_gemma":[0.00009896937,0.0001323995,0.0001878257,0.00006902277,0.0002673793,0.0001691059,0.0001645542,0.0005651459,0.0003217901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001927342,"about_ca_system_score_gemma":0.0002034471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002340742,"about_ca_topic_score_gemma":0.0004648757,"domain_scores_codex":[0.9998679,0.00002600078,0.00001512862,0.00002252206,0.0000195645,0.00004881887],"domain_scores_gemma":[0.9998852,0.000008097157,0.00004480851,0.000009311401,0.000007923766,0.00004464024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00111032,0.0002845319,0.0008244019,0.00007227528,0.00001180771,0.00004555633,0.00001104768,0.0000647759,0.9950363,0.00005505949,0.00008421407,0.002399557],"study_design_scores_gemma":[0.0005411619,0.01112639,0.03257124,0.00004138102,0.0001473445,0.001257728,0.000105817,0.001642778,0.9489591,0.0001195619,0.00347545,0.00001209627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998017,0.0007337397,0.0005139146,0.00008794684,0.0000248431,0.00002471495,0.00009330731,0.00005950389,0.0004450944],"genre_scores_gemma":[0.9959564,0.0006145348,0.001547257,0.00008252233,0.0000293521,0.00005123507,0.0002302349,0.00002011678,0.001468414],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001539839,"threshold_uncertainty_score":0.005151212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01542360660668238,"score_gpt":0.2584296711750492,"score_spread":0.2430060645683668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}