{"id":"W2012456279","doi":"10.2165/00003088-200746060-00002","title":"A Systematic Review of Limited Sampling Strategies for Platinum Agents Used in Cancer Chemotherapy","year":2007,"lang":"en","type":"review","venue":"Clinical Pharmacokinetics","topic":"Chemotherapy-induced organ toxicity mitigation","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's & Women's Health Centre of British Columbia; University of British Columbia","funders":"","keywords":"Medicine; Carboplatin; Pharmacokinetics; Dosing; Nedaplatin; Pharmacology; Pharmacodynamics; Blood sampling; Cisplatin; Body surface area; Therapeutic drug monitoring; Drug; Oncology; Area under the curve; Intensive care medicine; Chemotherapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002358206,0.0006158247,0.006081526,0.000313561,0.00002432106,0.00002057183,0.0003624097,0.0006604368,0.0002220802],"category_scores_gemma":[0.001363699,0.000505336,0.001323279,0.0008472295,0.0001394021,0.00005597361,0.00004115345,0.0009579826,0.00001002141],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002895566,"about_ca_system_score_gemma":0.0007509381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006643645,"about_ca_topic_score_gemma":0.000004333294,"domain_scores_codex":[0.9932762,0.000304227,0.004856242,0.0006230396,0.0005070919,0.0004332424],"domain_scores_gemma":[0.9938148,0.002772903,0.002243933,0.0006469502,0.0003014467,0.0002199542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00004948958,0.0003803908,0.00001805197,0.9003472,0.0006619935,0.000006351048,0.00005862862,0.000001047905,0.00005329455,0.000007009065,0.0007156881,0.09770086],"study_design_scores_gemma":[0.003246959,0.0002240143,0.00001547432,0.8923331,0.005729814,0.00001380421,0.00002511379,0.0001224274,0.0001686246,0.00003121871,0.09767753,0.000411926],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003302875,0.9885267,0.000625437,0.0001884844,0.0004309208,0.009639162,0.0001212122,0.00006150707,0.00007627343],"genre_scores_gemma":[0.00006415101,0.993894,0.001660999,0.002831829,0.0005996292,0.000387377,0.0002591559,0.000189444,0.0001133499],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.09728893,"threshold_uncertainty_score":0.9997398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.342529293198814,"score_gpt":0.5544087444008821,"score_spread":0.211879451202068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}