{"id":"W2012470778","doi":"10.1016/j.molimm.2006.09.025","title":"Prohibitin binds to C3 and enhances complement activation","year":2006,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Prohibitin; Immunoprecipitation; Chemistry; Complement system; Lysis; Molecular mass; Biochemistry; Molecular biology; Biology; Mitochondrion; Antibody; Enzyme; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003875803,0.0004689863,0.0003636464,0.0004850261,0.0004355918,0.0006718762,0.000423624,0.0004364625,0.005263993],"category_scores_gemma":[0.0004311818,0.0003147538,0.0003866456,0.0002315345,0.0004723785,0.0002684954,0.0005309458,0.001046559,0.001119723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001131937,"about_ca_system_score_gemma":0.0004905274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003076895,"about_ca_topic_score_gemma":0.0054616,"domain_scores_codex":[0.99943,0.0001149858,0.00003319108,0.00005566066,0.0001649994,0.0002010204],"domain_scores_gemma":[0.9994704,0.0001561071,0.00005613972,0.00009277926,0.00005022978,0.0001743157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005299181,0.00008049828,0.0001460283,0.00003694164,0.00001138059,0.00005038554,0.000008838944,0.00005239787,0.9975492,0.0002532475,0.0001443458,0.001136838],"study_design_scores_gemma":[0.00002514333,0.0001233183,0.002607881,0.00000342777,0.000009513452,0.0001516742,0.00001262107,0.0003477052,0.994754,0.00006024678,0.001899408,0.000005090888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988419,0.002434717,0.002523275,0.0004634912,0.0002153396,0.0000380084,0.0003012936,0.0001930762,0.005411762],"genre_scores_gemma":[0.9879556,0.0006053032,0.001183928,0.0001743169,0.00005410648,0.00002547822,0.0003525941,0.00003881091,0.009609881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005263993,"threshold_uncertainty_score":0.01760978,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004212903533895948,"score_gpt":0.2167012813793868,"score_spread":0.2124883778454909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}