{"id":"W2012494736","doi":"10.1210/en.2004-0544","title":"Role of Calcium-Calmodulin-Dependent Protein Kinase Cascade in Thyrotropin (TSH)-Releasing Hormone Induction of TSH and Prolactin Gene Expression","year":2004,"lang":"en","type":"article","venue":"Endocrinology","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Internal medicine; Endocrinology; Prolactin; Protein kinase A; Thyrotropin-releasing hormone; Signal transduction; Biology; Calmodulin; Kinase; Hormone; Medicine; Calcium; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008680687,0.0003013501,0.0002912045,0.0001625512,0.0002581779,0.0003075718,0.0001756213,0.0002958826,0.001178459],"category_scores_gemma":[0.00009556106,0.0001467147,0.0002798903,0.00007237903,0.0001601498,0.0002215112,0.0002229661,0.0003960317,0.000293093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004581041,"about_ca_system_score_gemma":0.0003793802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001272999,"about_ca_topic_score_gemma":0.001968047,"domain_scores_codex":[0.9999193,0.00001167249,0.000006231402,0.00001743093,0.00001772448,0.00002759953],"domain_scores_gemma":[0.9999412,0.000009990368,0.000011586,0.000003634956,0.00001063961,0.00002302109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001352466,0.0000311835,0.0003919716,0.00007418272,0.00000377403,0.0001839007,0.00001820054,0.00005483366,0.9975603,0.0001682109,0.00006012899,0.001318083],"study_design_scores_gemma":[0.0003137663,0.0007152926,0.07035431,0.0000452194,0.0000679925,0.001466755,0.0001537651,0.01023643,0.9099809,0.0007224368,0.00591445,0.00002866966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787597,0.01073479,0.004062926,0.0003909531,0.0001211658,0.0001193046,0.0003868736,0.0001447222,0.005279543],"genre_scores_gemma":[0.9939282,0.002226743,0.001717957,0.0000706002,0.00002356775,0.0000486654,0.0002083558,0.000008284499,0.00176756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001272999,"threshold_uncertainty_score":0.00394237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01653096512130057,"score_gpt":0.2574934530743735,"score_spread":0.240962487953073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}