{"id":"W2012511424","doi":"10.1046/j.1365-2958.2001.02404.x","title":"Physiological consequences of blocked <i>Caulobacter crescentus dnaA</i> expression, an essential DNA replication gene","year":2001,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Caulobacter crescentus; DnaA; Biology; DNA replication; Transcription (linguistics); Cell cycle; Cell division; Origin of replication; Cell biology; Origin recognition complex; Control of chromosome duplication; Pre-replication complex; Molecular biology; Genetics; Gene; Eukaryotic DNA replication; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001596907,0.0002595178,0.0003207092,0.00006561535,0.00007177944,0.00001447777,0.0004903012,0.0006857649,0.00007343719],"category_scores_gemma":[0.00006481467,0.0002252,0.0001390549,0.0001292009,0.0006508534,0.000004120772,0.0002556688,0.0001309656,0.00001113685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001034703,"about_ca_system_score_gemma":0.00006184762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001868246,"about_ca_topic_score_gemma":0.000008714119,"domain_scores_codex":[0.9980454,0.0002307816,0.00042285,0.0008426526,0.00005467963,0.0004036805],"domain_scores_gemma":[0.9985099,0.000005638409,0.0002331047,0.001012708,0.0001483005,0.00009030645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002133353,0.0001920184,0.0003525201,0.000006861116,0.00004782777,0.00001607119,0.00001097806,0.000009604632,0.9981092,0.00008643563,0.0003612343,0.0005939277],"study_design_scores_gemma":[0.0005555656,0.0007016869,0.0006193415,0.000008095355,0.00002436976,0.0002395152,0.00001520591,0.000003014765,0.9756904,0.0001430678,0.02173934,0.0002603778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973093,0.0005252017,0.001197361,0.0003015548,0.0002136392,0.0002665017,0.00007304255,0.00003260305,0.00008076607],"genre_scores_gemma":[0.9956898,0.000398813,0.001956352,0.0005384304,0.0001595513,0.00002473213,0.001141038,0.00002520189,0.00006605561],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02241876,"threshold_uncertainty_score":0.918339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008276265642654384,"score_gpt":0.2377744100018176,"score_spread":0.2294981443591632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}