{"id":"W2012576981","doi":"10.1016/j.semcancer.2015.02.007","title":"Cancer prevention and therapy through the modulation of the tumor microenvironment","year":2015,"lang":"en","type":"review","venue":"Seminars in Cancer Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":389,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; Dalhousie University","funders":"Thales Group; Ministerstvo Zdravotnictví Ceské Republiky; Ministry of Education, Culture, Sports, Science and Technology; Grantová Agentura České Republiky; Center for Hierarchical Manufacturing, National Science Foundation; University of Glasgow; Univerzita Karlova v Praze; Marie Curie; National Cancer Institute; National Institutes of Health; Cancer Research UK","keywords":"Tumor microenvironment; Angiogenesis; Cancer research; Carcinogenesis; Tumor hypoxia; Biology; Cancer; Immunology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001955453,0.0002140836,0.0007519854,0.00003466635,0.00003769981,0.000002668169,0.0001655633,0.0001785702,0.0001121611],"category_scores_gemma":[0.000008453469,0.0001017402,0.0001763061,0.0001508744,0.000293811,0.00001946177,0.00006305364,0.0002361633,0.00000128086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002175635,"about_ca_system_score_gemma":0.0003658445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002649951,"about_ca_topic_score_gemma":0.00003494832,"domain_scores_codex":[0.998859,0.0002421906,0.0003615303,0.0002723453,0.0001017623,0.0001631626],"domain_scores_gemma":[0.999166,0.00005314149,0.0003602096,0.0003734456,0.00002150748,0.00002572622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005072766,0.00006664287,0.0008010591,0.0007674197,0.0001721345,0.00000130722,0.0002417387,0.000004623707,0.00008437582,0.00003575652,0.0004694552,0.9973047],"study_design_scores_gemma":[0.0005638701,0.0001540366,0.001246092,0.0063872,0.0002903014,0.0000177406,0.00003163467,0.000007566611,0.0001248878,0.001176217,0.9898911,0.0001094018],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01313311,0.9847966,0.000003750542,0.0002560783,0.0003664609,0.001282794,0.00007537698,0.000005333895,0.00008051223],"genre_scores_gemma":[0.001926966,0.996613,0.00002845179,0.0002911682,0.0001833219,0.0005229732,0.00003709591,0.00002392574,0.0003731325],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9971954,"threshold_uncertainty_score":0.4148844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05697428158445467,"score_gpt":0.401980810122917,"score_spread":0.3450065285384624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}