{"id":"W2012634286","doi":"10.1016/j.mcn.2013.07.006","title":"Fluoxetine and citalopram decrease microglial release of glutamate and d-serine to promote cortical neuronal viability following ischemic insult","year":2013,"lang":"en","type":"article","venue":"Molecular and Cellular Neuroscience","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":74,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Innovates - Health Solutions","keywords":"Microglia; Monoamine neurotransmitter; Pharmacology; Glutamate receptor; Neuroprotection; Biology; Neuroscience; Serotonin; Inflammation; Immunology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002239719,0.0002667462,0.0002601375,0.0001207042,0.000261844,0.0002002754,0.0002121853,0.00005598539,0.00002044141],"category_scores_gemma":[0.001842259,0.000256616,0.00006160724,0.0003760783,0.0003131632,0.0003161983,0.0003406149,0.000213498,0.000007453322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006829746,"about_ca_system_score_gemma":0.00004602899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001366641,"about_ca_topic_score_gemma":7.192164e-7,"domain_scores_codex":[0.997557,0.0002188298,0.0004199524,0.000986336,0.0004388298,0.0003790178],"domain_scores_gemma":[0.9987679,0.00008009221,0.0001049214,0.000347307,0.00005506554,0.0006447405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000297014,0.00006984885,0.0001692706,0.00003514182,6.667671e-7,0.0001204507,0.00005595441,0.00001626712,0.997894,0.0005614263,0.000007959304,0.001039312],"study_design_scores_gemma":[0.0005050381,0.0003009284,0.00161602,0.00001199935,0.00001421919,0.0001290324,0.000006296485,0.007055597,0.9896634,0.0001807686,0.0002893235,0.0002273277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955081,0.00002735328,0.002760728,0.0006593735,0.0001780403,0.0007141753,0.00001412725,0.0000683898,0.00006969212],"genre_scores_gemma":[0.9964066,0.00002287761,0.0008227224,0.002596686,0.00001455362,0.00002862402,0.000001728749,0.00002679304,0.00007948838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008230551,"threshold_uncertainty_score":0.9999886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009847277856074695,"score_gpt":0.2209582088756134,"score_spread":0.2111109310195387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}