{"id":"W2012680073","doi":"10.1371/journal.pone.0015301","title":"A Porcine Adenovirus with Low Human Seroprevalence Is a Promising Alternative Vaccine Vector to Human Adenovirus 5 in an H5N1 Virus Disease Model","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Canadian Science Centre for Human and Animal Health; University of Manitoba; Public Health Agency of Canada","funders":"Canadian Institutes of Health Research; Public Health Agency; Public Health Agency of Canada","keywords":"Virology; Vaccination; Immune system; Influenza A virus subtype H5N1; Antibody; Viral vector; Neutralizing antibody; Vector (molecular biology); Biology; Inactivated vaccine; Virus; Immunology; Medicine; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002742062,0.0003231585,0.0001864395,0.0001863897,0.0001188529,0.0003311633,0.0001645023,0.0002747039,0.0007624475],"category_scores_gemma":[0.0001162243,0.0001041504,0.0002286863,0.0001142167,0.0002059948,0.0002895501,0.0001256855,0.0003560289,0.0001777455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003187678,"about_ca_system_score_gemma":0.0002087873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005594371,"about_ca_topic_score_gemma":0.0006142854,"domain_scores_codex":[0.9998676,0.0000347074,0.00001040754,0.00003011121,0.00003299075,0.00002417937],"domain_scores_gemma":[0.9999406,0.00001362434,0.00001982188,0.00000764063,0.000006825192,0.00001149518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000166846,0.00006070944,0.0005831047,0.000073132,0.000007701737,0.00004809575,0.00001367844,0.0002209488,0.9945963,0.0002705426,0.00006611463,0.00389283],"study_design_scores_gemma":[0.00004631257,0.005309306,0.009802024,0.00002689599,0.0000575688,0.001003501,0.00007154065,0.003443274,0.9708573,0.0003102112,0.009055384,0.0000167885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777199,0.003284782,0.0161186,0.0002112529,0.00009145058,0.0001068057,0.0003023649,0.0001010397,0.002063836],"genre_scores_gemma":[0.9874134,0.001399298,0.00870965,0.00004669867,0.00001149938,0.00005082855,0.000475022,0.000008389658,0.001885062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007624475,"threshold_uncertainty_score":0.002550602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03905710066214887,"score_gpt":0.3126203485135429,"score_spread":0.273563247851394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}