{"id":"W2012680073","doi":"10.1371/journal.pone.0015301","title":"A Porcine Adenovirus with Low Human Seroprevalence Is a Promising Alternative Vaccine Vector to Human Adenovirus 5 in an H5N1 Virus Disease Model","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Canadian Science Centre for Human and Animal Health; University of Manitoba; Public Health Agency of Canada","funders":"Canadian Institutes of Health Research; Public Health Agency; Public Health Agency of Canada","keywords":"Virology; Vaccination; Immune system; Influenza A virus subtype H5N1; Antibody; Viral vector; Neutralizing antibody; Vector (molecular biology); Biology; Inactivated vaccine; Virus; Immunology; Medicine; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002749462,0.0003818118,0.0003706936,0.0002237028,0.0001983436,0.00008309442,0.000701608,0.0001508544,0.0001924398],"category_scores_gemma":[0.00006692832,0.000360882,0.00006199905,0.0002904108,0.00009026979,0.00002971222,0.000223173,0.0004935727,0.00003615193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000629523,"about_ca_system_score_gemma":0.000206604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001586227,"about_ca_topic_score_gemma":0.005147318,"domain_scores_codex":[0.9972764,0.000110471,0.0003558138,0.0009823062,0.0006344642,0.0006405507],"domain_scores_gemma":[0.9978803,0.000009538986,0.0001189727,0.001128653,0.0002835998,0.0005789331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004469782,0.001810921,0.008556306,0.0001063299,0.000138733,0.00005038146,0.0003457612,0.0004376631,0.9838638,0.00001693641,0.00004354998,0.0001598033],"study_design_scores_gemma":[0.002217949,0.004367772,0.0067516,0.0001881043,0.00006349746,0.000002363,0.0000198153,0.004592152,0.9811594,0.0001131349,0.000007710606,0.0005164471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979723,0.0001669695,0.0000774649,0.0003270192,0.0000145318,0.001150829,0.000177298,0.00004117358,0.00007240966],"genre_scores_gemma":[0.9967332,0.00003608104,0.001043949,0.0007201675,0.0003485237,0.0002372413,0.0001178512,0.0001155397,0.0006473978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004988696,"threshold_uncertainty_score":0.9998843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03905710066214887,"score_gpt":0.3126203485135429,"score_spread":0.273563247851394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}