{"id":"W2012715950","doi":"10.1016/j.jaad.2010.12.005","title":"Long-term efficacy and safety of adalimumab in patients with moderate to severe psoriasis treated continuously over 3 years: Results from an open-label extension study for patients from REVEAL","year":2011,"lang":"en","type":"article","venue":"Journal of the American Academy of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":177,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre de Recherche Dermatologique du Québec Métropolitain; Probity Medical Research","funders":"","keywords":"Adalimumab; Medicine; Psoriasis Area and Severity Index; Psoriasis; Adverse effect; Placebo; Internal medicine; Open label; Clinical trial; Randomized controlled trial; Severity of illness; Surgery; Dermatology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002359863,0.0009250979,0.001982264,0.0004138839,0.0006278136,0.00101498,0.0005010818,0.00101648,0.001428433],"category_scores_gemma":[0.001626949,0.0004501709,0.002059109,0.0004349254,0.000769367,0.001140133,0.0003608037,0.002305423,0.0004041057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005402435,"about_ca_system_score_gemma":0.0005753376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001109069,"about_ca_topic_score_gemma":0.001567066,"domain_scores_codex":[0.9991606,0.0003481893,0.00006715996,0.000130682,0.0001030244,0.0001902685],"domain_scores_gemma":[0.9985312,0.0003597917,0.0003971978,0.0001750028,0.0001024864,0.0004342143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8535629,0.01901153,0.05979707,0.0003744843,0.002197497,0.0002246748,0.0004148362,0.0006417782,0.0157705,0.00007703754,0.0006816858,0.04724599],"study_design_scores_gemma":[0.304377,0.3611154,0.3228106,0.00006884876,0.003990467,0.0004829944,0.0002936648,0.001362517,0.003262839,0.0001640884,0.00197467,0.00009702585],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985317,0.0007633468,0.00008396627,0.0000548622,0.0000246769,0.00008200492,0.0002100095,0.00001018238,0.0002392969],"genre_scores_gemma":[0.998315,0.0003508486,0.0001847804,0.0001281798,0.0000751343,0.0001107623,0.000417442,0.000005919489,0.0004119773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002359863,"threshold_uncertainty_score":0.01248032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02743260900518708,"score_gpt":0.2852208799279339,"score_spread":0.2577882709227468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}