{"id":"W2012723527","doi":"10.1016/j.cgh.2014.06.011","title":"Fecal Calprotectin–Guided Dosing of Mesalamine in Ulcerative Colitis: Concept Proved but More Data Needed","year":2014,"lang":"en","type":"letter","venue":"Clinical Gastroenterology and Hepatology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Genentech; Vlaamse regering; Optimer Pharmaceuticals; Shire; Bristol-Myers Squibb; Orexigen Therapeutics; UCB; Roche; Novartis; Merck; GlaxoSmithKline; Pfizer; Janssen Pharmaceuticals; Gilead Sciences; Boehringer Ingelheim","keywords":"Medicine; Calprotectin; Ulcerative colitis; Dosing; Gastroenterology; Internal medicine; Feces; Inflammatory bowel disease; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002037074,0.0005068127,0.001690841,0.0003933548,0.0009116807,0.001699029,0.001183564,0.01583273,0.002300146],"category_scores_gemma":[0.0127545,0.0002573129,0.001059738,0.0003844865,0.001832631,0.00173448,0.0004903287,0.01635772,0.001844425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00255032,"about_ca_system_score_gemma":0.001427617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001496987,"about_ca_topic_score_gemma":0.002782553,"domain_scores_codex":[0.9982681,0.0007472843,0.0002816562,0.0001265695,0.0004199467,0.0001563606],"domain_scores_gemma":[0.9934477,0.004011672,0.0004918844,0.0002069887,0.001056476,0.0007853336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003052271,0.0006009814,0.005396364,0.0003977203,0.0002171976,0.01810759,0.0001513706,0.0007187416,0.00273239,0.007570516,0.7729781,0.1880768],"study_design_scores_gemma":[0.00545329,0.0028752,0.01348532,0.001549687,0.0004126738,0.02197508,0.0004133743,0.006644867,0.003571578,0.03697315,0.9064221,0.0002235599],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.00318416,0.007126916,0.0006832177,0.9707163,0.01382283,0.00002787909,0.00005007442,0.00005596448,0.004332617],"genre_scores_gemma":[0.04975799,0.008704396,0.002733241,0.8015842,0.1291038,0.0001141691,0.0001021027,0.0000435768,0.007856435],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01583273,"threshold_uncertainty_score":0.01850396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04662111259574328,"score_gpt":0.337606989294262,"score_spread":0.2909858766985187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}