{"id":"W2012802180","doi":"10.1245/s10434-012-2858-5","title":"Risk of Metachronous Colon Cancer Following Surgery for Rectal Cancer in Mismatch Repair Gene Mutation Carriers","year":2013,"lang":"en","type":"article","venue":"Annals of Surgical Oncology","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":123,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Cancer Institute","keywords":"Medicine; Colorectal cancer; Lynch syndrome; Internal medicine; MLH1; Cancer; Oncology; Colonoscopy; Germline mutation; Surgical oncology; Colectomy; Gastroenterology; Mutation; DNA mismatch repair","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008633102,0.0001893323,0.001146899,0.0002065547,0.00003533455,0.000003100508,0.0000855041,0.000319408,0.0005393916],"category_scores_gemma":[0.0002953229,0.0001669941,0.0005890949,0.0003481107,0.000168861,0.00007390702,0.00003479807,0.0002086665,0.000002646849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002666478,"about_ca_system_score_gemma":0.0009500892,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008457464,"about_ca_topic_score_gemma":0.001256879,"domain_scores_codex":[0.9978691,0.0002258095,0.0008334423,0.0003589433,0.0002779242,0.0004347308],"domain_scores_gemma":[0.9971541,0.001581456,0.0004475058,0.0002050315,0.0004478899,0.0001639915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00792229,0.001402577,0.6139984,0.001156689,0.003447416,0.0004889727,0.003035789,0.005307377,0.05271606,0.00003555357,0.03459376,0.2758951],"study_design_scores_gemma":[0.01300485,0.008467379,0.3903522,0.0008885826,0.001777825,0.0001476742,0.001196961,0.007038461,0.4530683,0.001058976,0.121818,0.001180769],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893976,0.00494184,0.00001693361,0.003173737,0.0008509107,0.001042991,0.0000968732,0.00003003082,0.0004490658],"genre_scores_gemma":[0.9919116,0.005810592,0.0009357925,0.0002018733,0.0001445567,0.0008188411,0.0000207065,0.00003079457,0.0001252192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4003523,"threshold_uncertainty_score":0.9981453,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05670832348529644,"score_gpt":0.3801274232854083,"score_spread":0.3234190998001119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}