{"id":"W2012859709","doi":"10.1007/s11095-009-9951-x","title":"Characterization of a Microsphere Formulation Containing Glucose Oxidase and its In Vivo Efficacy in a Murine Solid Tumor Model","year":2009,"lang":"en","type":"article","venue":"Pharmaceutical Research","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"In vivo; Microsphere; Glucose oxidase; Chemistry; Solid tumor; Pharmaceutical technology; Pharmacology; Medicine; Biochemistry; Biology; Enzyme; Cancer; Internal medicine; Chromatography; Biotechnology; Chemical engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002846514,0.0002661605,0.0001589086,0.0001946015,0.0001208549,0.0001302378,0.0001783354,0.0002717317,0.0004993011],"category_scores_gemma":[0.0002325351,0.0001054432,0.0001815024,0.0001110218,0.0001579514,0.0002262069,0.00006672047,0.0003036651,0.0001100783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002069114,"about_ca_system_score_gemma":0.0001815318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009228362,"about_ca_topic_score_gemma":0.0007481032,"domain_scores_codex":[0.9999207,0.00001216677,0.000005444939,0.00002150833,0.00002294841,0.00001714752],"domain_scores_gemma":[0.9998345,0.00004337269,0.0000550917,0.00001131861,0.00002981743,0.00002593443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006370476,0.00001468372,0.00004384661,0.00000885348,0.000001821756,0.0000118827,0.000004541731,0.0000420809,0.9992144,0.00002002786,0.000007459474,0.0005666341],"study_design_scores_gemma":[0.000005171667,0.0003290304,0.0005986249,7.783642e-7,0.000007521008,0.00003464593,0.000002321511,0.0003507295,0.9984251,0.000005067253,0.0002395666,0.000001521109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850578,0.0008807313,0.01312707,0.00006488728,0.00002695667,0.00006521347,0.0002043658,0.00006915593,0.0005038079],"genre_scores_gemma":[0.988941,0.000416318,0.008951018,0.00002859398,0.0000145246,0.00003796046,0.0002638443,0.00003191252,0.001314888],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009228362,"threshold_uncertainty_score":0.001834989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2404391843371592,"score_gpt":0.5334837759223248,"score_spread":0.2930445915851656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}